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001-es BibID:BIBFORM082451
Első szerző:Turel, Iztok
Cím:Interactions of oxovanadium(IV) and the quinolone family member : ciprofloxacin / Iztok Turel, Amalija Golobič, Aleš Klavžar, Boris Pihlar, Péter Buglyó, Evangelos Tolis, Dieter Rehder, Kristina Sepčić
Dátum:2003
ISSN:0162-0134
Megjegyzések:The interactions of quinolone ciprofloxacin (cfH) and oxovanadium(IV) were studied by various methods. Green crystals of a complex [VIVO(cf)2(H2O)] were isolated and the molecular connectivities established, although the crystal structure was not perfectly refined due to the instability of the crystals. Based on a plausible interpretation of the data sets, two cf anions bidentately coordinate to a vanadyl cation through carboxylate and carbonyl oxygen atoms; in addition, there is a water molecule in the coordination sphere. Solution techniques (cyclic voltammetry, electronic and electron paramagnetic resonance spectroscopy, potentiometric measurements) confirmed the presence of various species in the solution, the composition of which strongly depends on the conditions in the system. The antibacterial activity of the complex against various microorganisms was tested and it was established that its activity is similar to that of free ciprofloxacin.
Tárgyszavak:Természettudományok Kémiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Journal of Inorganic Biochemistry. - 95 : 2-3 (2003), p. 199-207. -
További szerzők:Golobič, Amalija Klavžar, Aleš Pihlar, Boris Buglyó Péter (1965-) (vegyész) Tolis, Evangelos Rehder, Dieter Sepčić, Kristina
Pályázati támogatás:OTKA F32235
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