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001-es BibID:	BIBFORM099403
Első szerző:	Bálint István Bence
Cím:	Is duodeno-jejunal bypass liner superior to pylorus preserving bariatric surgery in terms of complications and efficacy? / Istvan Bence Bálint, Ferenc Csaszar, Krisztián Somodi, László Ternyik, Adrienn Biro, Zsolt Kaposztas
Dátum:	2021
ISSN:	1435-2443
Megjegyzések:	Purpose: Based on recent scientific evidence, bariatric surgery is more effective in the management of morbid obesity and related comorbidities than conservative therapy. Pylorus preserving surgical procedures (PPBS) such as laparoscopic single-anastomosis duodeno-jejunal or duodeno-ileal bypass with sleeve gastrectomy are modified duodenal switch (DS) surgical techniques. The duodeno-jejunal bypass liner (DJBL) is a novel surgical method in the inventory of metabolism focused manual interventions that excludes duodeno-jejunal mucosa from digestion, mimicking DS procedures without the risk of surgical intervention. The aim of this article is to summarize and compare differences between safety-related features and weight loss outcomes of DJBL and PPBS. Methods: A literature search was conducted in the PubMed database. Records of DJBL-related adverse events (AEs), occurrence of PPBS-related complications and reintervention rates were collected. Mean weight, mean body mass index (BMI), percent of excess of weight loss (EWL%), percent of total weight loss (TWL%) and BMI value alterations were recorded for weight loss outcomes. Results: A total of 11 publications on DJBL and 6 publications on PPBS were included, involving 800 and 1462 patients, respectively. The baseline characteristics of the patients were matched. Comparison of DJBL-related AEs and PPBS-related severe complications showed an almost equal risk (risk difference (RD): ?0.03 and confidence interval (CI): ?0.27 to 0.21), despite higher rates among patients having received endoscopic treatment. Overall AE and complication rates classified by Clavien-Dindo showed that PPBS was superior to DJBL due to an excess risk level of 25% (RD: 0.25, CI: 0.01?0.49). Reintervention rates were more favourable in the PPBS group, without significant differences in risk (RD: ?0.03, CI: ?0.27 to 0.20). However, PPBS seemed more efficient regarding weight loss outcomes at 1-year follow-up according to raw data, while meta-analysis did not reveal any significant difference (odds ratio (OR): 1.08, CI: 0.74?1.59 for BMI changes).
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Pylorus preserving Bariatric surgery Metabolic surgery Single-anastomosis duodeno-jejunal bypass Single-anastomosis duodeno-ileal bypass Duodenal switch Duodeno-jejunal bypass liner EndoBarrier
Megjelenés:	Langenbecks Archives Of Surgery. - 406 : 5 (2021), p. 1363-1377. -
További szerzők:	Császár Ferenc Somodi Krisztián Ternyik László Biró Adrienn (1988-) (orvos) Káposztás Zsolt
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