Találati lista | Tudóstér

001-es BibID:	BIBFORM103329
035-os BibID:	(WOS)000562983300018 (Scopus)85089709649
Első szerző:	Simon Fruzsina (vegyész)
Cím:	The chlorination of N-methyl amino acids with hypochlorous acid: kinetics and mechanisms / Fruzsina Simon, Eszter Kiss, Mária Szabó, István Fábián
Dátum:	2020
ISSN:	0893-228X
Megjegyzések:	The formation and decomposition kinetics of N-chloro-N-methyl amino acids were studied to predict the fate and impact of these compounds in water treatment technologies and biological systems. These compounds form in fast second-order reactions between N-methyl amino acids and hypochlorous acid. The comparison of the activation parameters for the reactions of N-methyl substituted and nonsubstituted branched-chain amino acids reveals the transition-state features less organized structure and stronger bonds between the reactants in the reactions with the N-methyl derivatives. This is due to a combined positive inductive effect of the N-methyl group and the alkyl side chain as well as to the steric effects of the substituents. N-Methyl-N-chloro amino acids decompose much faster than the nonsubstituted compounds. The reaction rates do not depend on the pH, and the same final product is formed in the entire pH range. N-Chlorosarcosine is an exception, as it decomposes via competing paths, k(d)(obs) = k(d) + k(d)(OH)[OH-], yielding different final products. This feature is most likely due to the lack of an alkyl substituent on the alpha-carbon atom. Under physiological pH, aldehydes and methylamine form in these reactions, which are not particularly toxic.
Tárgyszavak:	Természettudományok Kémiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Chemical Research In Toxicology. - 33 : 8 (2020), p. 2189-2196. -
További szerzők:	Kiss Eszter (1995-) Szabó Mária (1991-) (vegyész) Fábián István (1956-) (vegyész)
Pályázati támogatás:	GINOP-2.3.2-15-2016-00008 GINOP K-124983 OTKA ÚNKP-19-3 Egyéb
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon: