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001-es BibID:	BIBFORM109571
035-os BibID:	(cikkazonosító)5147 (WoS)000955708300001 (Scopus)85151114076
Első szerző:	Máthé Csaba (biológus)
Cím:	"B" Regulatory Subunits of PP2A: Their Roles in Plant Development and Stress Reactions / Máthé Csaba, Freytag Csongor, Kelemen Adrienn, M-Hamvas Márta, Garda Tamás
Dátum:	2023
ISSN:	1422-0067
Megjegyzések:	Protein phosphatase PP2A is an enzyme complex consisting of C (catalytic), A (scaffold) and B (regulatory) subunits. B subunits are a large family of proteins that regulate activity, substrate specificity and subcellular localization of the holoenzyme. Knowledge on the molecular functions of PP2A in plants is less than for protein kinases, but it is rapidly increasing. B subunits are responsible for the large diversity of PP2A functioning. This paper intends to give a survey on their multiple regulatory mechanisms. Firstly, we give a short description on our current knowledge in terms of "B"- mediated regulation of metabolic pathways. Next, we present their subcellular localizations, which extend from the nucleus to the cytosol and membrane compartments. The next sections show how B subunits regulate cellular processes from mitotic division to signal transduction pathways, including hormone signaling, and then the emerging evidence for their regulatory (mostly modulatory) roles in both abiotic and biotic stress responses in plants. Knowledge on these issues should be increased in the near future, since it contributes to a better understanding of how plant cells work, it may have agricultural applications, and it may have new insights into how vascular plants including crops face diverse environmental challenges.
Tárgyszavak:	Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk protein phosphatase PP2A B subunit subcellular localization metabolism development signal transduction abiotic stress biotic stress
Megjelenés:	International Journal Of Molecular Sciences. - 24 : 6 (2023), p. 1-13. -
További szerzők:	Freytag Csongor (1993-) (biológus) Kelemen Adrienn (1995-) (Biológus) Mikóné Hamvas Márta (1963-) (biológus) Garda Tamás (1990-) (biológus)
Pályázati támogatás:	OTKA-120638 OTKA ÚNKP-22-4-I-DE-11 Egyéb
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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