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001-es BibID:	BIBFORM111406
035-os BibID:	(cikkazonosító)7449 (Scopus)85158154745 (WoS)001001538500018
Első szerző:	Boutry, Justine
Cím:	Spontaneously occurring tumors in different wild-derived strains of hydra / Justine Boutry, Marie Buysse, Sophie Tissot, Chantal Cazevielle, Rodrigo Hamede, Antoine M. Dujon, Beata Ujvari, Mathieu Giraudeau, Alexander Klimovich, Frédéric Thomas, Jácint Tökölyi
Dátum:	2023
ISSN:	2045-2322
Megjegyzések:	Hydras are freshwater cnidarians widely used as a biological model to study diferent questions such as senescence or phenotypic plasticity but also tumoral development. The spontaneous tumors found in these organisms have been so far described in two female lab strains domesticated years ago (Hydra oligactis and Pelmatohydra robusta) and the extent to which these tumors can be representative of tumors within the diversity of wild hydras is completely unknown. In this study, we examined individuals isolated from recently sampled wild strains of diferent sex and geographical origin, which have developed outgrowths looking like tumors. These tumefactions have common features with the tumors previously described in lab strains: are composed of an accumulation of abnormal cells, resulting in a similar enlargement of the tissue layers. However, we also found diversity within these new types of tumors. Indeed, not only females, but also males seem prone to form these tumors. Finally, the microbiota associated to these tumors is diferent from the one involved in the previous lineages exhibiting tumors. We found that tumorous individuals hosted yet undescribed Chlamydiales vacuoles. This study brings new insights into the understanding of tumor susceptibility and diversity in brown hydras from diferent origins.
Tárgyszavak:	Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Scientific Reports. - 13 : 1 (2023), p. 1-11. -
További szerzők:	Buysse, Marie Tissot, Sophie Cazevielle, Chantal Hamede, Rodrigo Dujon, Antoine M. Ujvári Beáta Giraudeau, Mathieu Klimovich, Alexander Thomas, Frédéric Tökölyi Jácint (1984-) (biológus)
Pályázati támogatás:	MTA-DE Lendület LP2021/12. MTA Élettudományok - Biológiai tudományok
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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