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001-es BibID:	BIBFORM115341
035-os BibID:	(WoS)001123624500001 (Scopus)85179364233
Első szerző:	Deibel, Elisabeth
Cím:	Does the impact of COVID-19 on patients with systemic sclerosis change over time? / Deibel Elisabeth, Carreira Patricia E., Vonk Madelon, del Papa Nicoletta, Becvár Radim, Guillén-Del-Castillo Alfredo, Campochiaro Corrado, Poormoghim Hadi, Liem Sophie, Lazzaroni Maria-Grazia, Giollo Alessandro, Mekinian Arsene, de Vries-Bouwstra Jeska, De Santis Maria, Balbir-Gurman Alexandra, Mihai Carina, De Luca Giacomo, Moiseev Sergey, Zanatta Elisabetta, Foti Rosario, Rednic Simona, Denton Christopher, Cutolo Maurizio, Belloli Laura, Airo Paolo, Garzanova Liudmila, Moroncini Gianluca, Inanc Murat, Panopoulos Stylianos, Tandaipan Jose-Luis, Chatelus Emmanuel, Rosato Edoardo, Kuwana Masataka, Yavuz Sule, Alegre-Sancho Juan J., Smith Vanessa, Szűcs Gabriella, Henes Jörg, Rodríguez-Pintó Ignasi, Atzeni Fabiola, Spierings Julia, Truchetet Marie-Elise, Milchert Marcin, Brito de Araujo Daniel, Riemekasten Gabriela, Bernardino Vera, Martin Thierry, del Galdo Francesco, Vacca Alessandra, Mendoza Fabian, Midtvedt Øyvind, Murdaca Giuseppe, Santiago Tania, Codullo Veronica, Cacciapaglia Fabio, Walker Ulrich, Brunborg Cathrine, Tirelli Francesca, Allanore Yannick, Furst Daniel E., Matucci Marco, Gabrielli Armando, Distler Oliver, Hoffmann-Vold Anna-Maria
Dátum:	2024
ISSN:	2151-464X 2151-4658
Megjegyzések:	Objective. The outcome of patients with COVID-19 improved over the pandemic, including patients with systemic rheumatic diseases. However, data on patients with systemic sclerosis (SSc) are lacking. This study aimed to assess the outcome of patients with both SSc and COVID-19 over several waves.Methods. Patients with both SSc and COVID-19 who were registered in the European Scleroderma Trials and Research group (EUSTAR) were collected between April 2020 and April 2021. Patients were assigned to waves 1, 2, or 3 depending on the date of their COVID-19 diagnosis. Primary endpoints were death, intensive care unit stay, or ventilatory support (severe outcome). Subgroup analyses of patients who were hospitalized or died were conducted. General and SSc-specific characteristics and treatment were compared over the waves. Descriptive statistics and multivariate logistic regression were applied.Results. A total of 333 patients were included; 57 patients (17%) had a severe outcome, and 30 patients (9%) died. Compared to wave 1, significantly fewer patients with SSc suffered from severe COVID-19 in waves 2 and 3 (28.2% vs 9.8% and 12.7%; P < 0.001), fewer patients required hospitalization (46.7% vs 19.6% and 25.5%; P < 0.001) or ventilatory support (24.0% vs 8.7% and 10.9%; P = 0.001), and fewer patients died (15.7% vs 5.0% and 7.5%; P = 0.011). Patients were significantly younger, more often men, had less frequent arterial hypertension, and less SSc cardiac involvement over waves 1 to 3. Patients received significantly less medium to high doses of corticosteroids as they did SSc treatment.Conclusion. The outcome of patients with both SSc and COVID-19 improved significantly over time because of intrinsic and extrinsic factors.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Arthritis Care And Research. - 76 : 1 (2024), p. 88-97. -
További szerzők:	Carreira, Patricia E. Vonk, Madelon C. del Papa, Nicoletta Becvar, Radim Guillén-Del-Castillo, Alfredo Campochiaro, Corrado Poormoghim, Hadi Liem, Sophie Lazzaroni, Maria-Grazia Giollo, Alessandro Mekinian, Arsene de Vries-Bouwstra, Jeska De Santis, Maria Balbir Gurman, Alexandra Mihai, Carina De Luca, Giacomo Moiseev, Sergey Zanatta, Elisabetta Foti, Rosario Rednic, Simona Denton, Christopher Cutolo, Maurizio Belloli, Laura Airò, Paolo Garzanova, Liudmila Moroncini, Gianluca Inanc, M. Panopoulos, Stylianos Tandaipan, José-Luis Chatelus, Emmanuel Rosato, Edoardo Kuwana, Masataka Yavuz, Sule Alegre-Sancho, Juan Jose Smith, Vanessa Szűcs Gabriella (1963-) (belgyógyász, allergológus és klinikai immunológus, reumatológus) Henes, Jörg Rodríguez-Pintó, Ignasi Atzeni, Fabiola Spierings, Julia Truchetet, Marie-Elise Milchert, Marcin Brito de Araujo, Daniel Riemekasten, Gabriela Bernardino, Vera Martin, Thierry del Galdo, Francesco Vacca, Alessandra Mendoza, Fabian A. Midtvedt, Øyvind Murdaca, Giuseppe Santiago, Tania Codullo, Veronica Cacciapaglia, Fabio Walker, Ulrich Brunborg, Cathrine Tirelli, Francesca Allanore, Yannick Furst, Daniel E. Matucci-Cerinic, Marco Gabrielli, Armando Distler, Oliver Hoffmann-Vold, Anna-Maria
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