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001-es BibID:	BIBFORM116181
035-os BibID:	(Scopus)85176106626
Első szerző:	Rossi, Giuseppe
Cím:	Age, successive waves, immunization, and mortality in elderly COVID-19 hematological patients : EPICOVIDEHA findings / Giuseppe Rossi, Jon Salmanton-García, Chiara Cattaneo, Francesco Marchesi, Julio Dávila-Valls, Sonia Martín-Pérez, Federico Itri, Alberto López-García, Andreas Glenthøj, Maria Gomes da Silva, Caroline Besson, Monia Marchetti, Barbora Weinbergerová, Ozren Jaksic, Moraima Jiménez, Yavuz M. Bilgin, Jaap Van Doesum, Francesca Farina, Pavel Žák, Luisa Verga, Graham P. Collins, Valentina Bonuomo, Jens Van Praet, Marcio Nucci, Stef Meers, Ildefonso Espigado, Nicola S. Fracchiolla, Toni Valković, Christian Bjørn Poulsen, Natasha Čolović, Giulia Dragonetti, Marie-Pierre Ledoux, Carlo Tascini, Caterina Buquicchio, Ola Blennow, Francesco Passamonti, Marina Machado, Jorge Labrador, Rafael F. Duarte, Martin Schönlein, Lucia Prezioso, Iker Falces-Romero, Austin Kulasekararaj, Carolina Garcia-Vidal, Noemí Fernández, Ghaith Abu-Zeinah, Irati Ormazabal-Vélez, Tatjana Adžić-Vukičević, Klára Piukovics, Igor Stoma, Annarosa Cuccaro, Gabriele Magliano, Tomáš Szotkowski, Tomás José González-López, Shaimaa El-Ashwah, Rui Bergantim, Uluhan Sili, Johan Maertens, Fatih Demirkan, Cristina De Ramón, Verena Petzer, Maria Ilaria Del Principe, Milan Navrátil, Michelina Dargenio, Guldane Cengiz Seval, Michail Samarkos, Zdeněk Ráčil, László Imre Pinczés, Tobias Lahmer, Alessandro Busca, Gustavo-Adolfo Méndez, Antonio Vena, Monika M. Biernat, Maria Merelli, Maria Calbacho, Aleksandra Barać, Martina Bavastro, Alessandro Limongelli, Osman Ilhan, Dominik Wolf, Gökçe Melis Çolak, Ramón García-Sanz, Ziad Emarah, Bojana Mišković, Stefanie K. Gräfe, Miloš Mladenović, Tommaso Francesco Aiello, Lucía Núñez-Martín-Buitrago, Anna Nordlander, Elena Arellano, Giovanni Paolo Maria Zambrotta, Emanuele Ammatuna, Alba Cabirta, Maria Vittoria Sacchi, Raquel Nunes Rodrigues, Ditte Stampe Hersby, Michaela Hanakova, Laman Rahimli, Raul Cordoba, Oliver A. Cornely, Livio Pagano
Dátum:	2023
ISSN:	1201-9712
Megjegyzések:	Objectives: Elderly patients with hematologic malignancies face the highest risk of severe COVID-19 outcomes. The infection's impact on different age groups remains unstudied in detail. Methods: We analyzed elderly patients (age groups: 65-70, 71-75, 76-80, and >80 years old) with hematologic malignancies included in the EPICOVIDEHA registry between January 2020 and July 2022. Univariable and multivariable Cox regression models were conducted to identify factors influencing death in COVID-19 patients with hematological malignancy. Results: The study included data from 3,603 elderly patients (aged 65 or older) with hematological malignancy, with a majority being male (58.1%) and a significant proportion having comorbidities. The patients were divided into four age groups, and the analysis assessed COVID-19 outcomes, vaccination status, and other variables in relation to age and pandemic waves. The 90-day survival rate for patients with COVID-19 was 71.2%, with significant differences between groups. The pandemic waves had varying impacts, with the first wave affecting patients over 80 years old, the second being more severe in 65-70, and the third being the least severe in all age groups. Factors contributing to 90-day mortality included age, comorbidities, lymphopenia, active malignancy, acute leukemia, less than three vaccine doses, severe COVID-19, and using only corticosteroids as treatment. Conclusion: These data underscore the heterogeneity of elderly hematological patients, highlight the different impacts of COVID-19 waves and the pivotal importance of vaccination, and may help in planning future healthcare efforts. ? 2023 The Author(s)
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk COVID-19 Elderly Hematological malignancy High-risk patient SARS-CoV-2
Megjelenés:	International Journal Of Infectious Diseases. - 137 (2023), p. 98-110. -
További szerzők:	Salmanton-García, Jon Cattaneo, Chiara Marchesi, Francesco Dávila-Valls, Julio Martín-Pérez, Sonia Itri, Federico López-García, Alberto Glenthj, Andreas Gomes Da Silva, Maria Besson, Caroline Marchetti, Monia Weinbergerová, Barbora Jaksic, Ozren Jiménez, Moraima Bilgin, Yavuz M. van Doesum, Jaap Farina, Francesca Žák, Pavel Verga, Luisa Collins, Graham Bonuomo, Valentina van Praet, Jens Nucci, Marcio Meers, Stef Espigado, Ildefonso Fracchiolla, Nicola S. Valkovic, Toni Poulsen, Christian Bjørn Colovic, Natasa Dragonetti, Giulia Ledoux, Marie-Pierre Tascini, Carlo Buquicchio, Caterina Blennow, Ola Passamonti, Francesco Machado, Marina Labrador, Jorge Duarte, Rafael F. Schönlein, Martin Prezioso, Lucia Falces-Romero, Iker Kulasekararaj, Austin Garcia-Vidal, Carolina Fernández, Noemí Abu-Zeinah, Ghaith Ormazabal-Vélez, Irati Adžić-Vukičević, Tatjana Piukovics Klára Stoma, Igor Cuccaro, Annarosa Magliano, Gabriele Szotkowski, Tomáš González-López, Tomás José El-Ashwah, Shaimaa Bergantim, Rui Sili, Uluhan Maertens, Johan Demirkan, Fatih De Ramón, Cristina Petzer, Verena Del Principe, Maria Ilaria Navrátil, Milan Dargenio, Michelina Seval, Guldane Cengiz Samarkos, Michail Ráčil, Zdenĕk Pinczés László Imre (1990-) (hematológus) Lahmer, Tobias Busca, Alessandro Méndez, Gustavo-Adolfo Vena, Antonio Biernat, Monika M. Merelli, Maria Calbacho, Maria Barać, Aleksandra Bavastro, Martina Limongelli, Alessandro Ilhan, Osman Wolf, Dominik Çolak, Gökçe Melis García-Sanz, Ramón Emarah, Ziad Mišković, Bojana Gräfe, Stefanie K. Mladenović, Miloš Aiello, Tommaso Francesco Núñez-Martín-Buitrago, Lucía Nordlander, Anna Arellano, Elena Zambrotta, Giovanni Paolo Maria Ammatuna, Emanuele Cabirta, Alba Sacchi, Maria Vittoria Rodrigues, Raquel Nunes Hersby, Ditte Stampe Hanáková, Michaela Rahimli, Laman Cordoba, Raul Cornely, Oliver Andreas Pagano, Livio
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