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001-es BibID:	BIBFORM117251
035-os BibID:	(Scopus)85178361033 (cikkazonosító)3504 (WoS)001122834800001
Első szerző:	Gál Bence
Cím:	A Snapshot on the Genomic Epidemiology of Turkey Reovirus Infections, Hungary / Bence Gál, Renáta Varga-Kugler, Katalin Ihász, Eszter Kaszab, Szilvia Farkas, Szilvia Marton, Vito Martella, Krisztián Bányai
Dátum:	2023
ISSN:	2076-2615
Megjegyzések:	Reovirus infections in turkeys are associated with arthritis and lameness. Viral genome sequence data are scarce, which makes an accurate description of the viral evolution and epidemiology difficult. In this study, we isolated and characterized turkey reoviruses from Hungary. The isolates were identified in 2016; these isolates were compared with earlier Hungarian turkey reovirus strains and turkey reoviruses isolated in the 2010s in the United States. Gene-wise sequence and phylogenetic analyses identified the cell-receptor binding protein and the main neutralization antigen, ?C, to be the most conserved. The most genetically diverse gene was another surface antigen coding gene, ?B. This gene was shown to undergo frequent reassortment among chicken and turkey origin reoviruses. Additional reassortment events were found primarily within members of the homologous turkey reovirus clade. Our data showed evidence for low variability among strains isolated from independent outbreaks, a finding that suggests a common source of turkey reoviruses in Hungarian turkey flocks. Given that commercial vaccines are not available, identification of the source of these founder virus strains would permit a more efficient prevention of disease outbreaks before young birds are settled to fattening facilities.
Tárgyszavak:	Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Avian orthoreovirus interspecies transmission phylogenetic analysis reassortment Spinareoviridae whole-genome sequencing
Megjelenés:	Animals. - 13 : 22 (2023), p. 1-12. -
További szerzők:	Varga-Kugler Renáta Ihász Katalin Kaszab Eszter (1989-) (biológus) Farkas Szilvia Marton Szilvia Martella, Vito Bányai Krisztián (virológus)
Pályázati támogatás:	RRF-2.3.1-21-2022-00001 Egyéb TKP2021-EGA-01 Egyéb
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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