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001-es BibID:	BIBFORM117255
035-os BibID:	(cikkazonosító)1281473 (WoS)001111568000001 (Scopus)85178472490
Első szerző:	Kaszab Eszter (biológus)
Cím:	Antimicrobial resistance genes and associated mobile genetic elements in Lactobacillales from various sources / Eszter Kaszab, Levente Laczkó, Gábor Kardos, Krisztián Bányai
Dátum:	2023
ISSN:	1664-302X
Megjegyzések:	Lactobacillales are commonly used in food products and as probiotics in animal and human medicine. Despite being generally recognized as safe, lactic acid bacteria may harbor a variety of antimicrobial resistance genes (ARGs), which may be transferable to human or veterinary pathogens, thus, may pose veterinary and public health concerns. This study investigates the resistome of Lactobacillales. A total of 4,286 whole-genome sequences were retrieved from NCBI RefSeq database. We screened ARGs in whole genome sequences and assessed if they are transmissible by plasmid transfer or by linkage to integrative mobile genetic elements. In the database, 335 strains were found to carry at least one ARG, and 194 strains carried at least one potentially transferable ARG. The most prevalent transferable ARG were tetM and tetW conferring antibiotic resistance to tetracycline. This study highlights the importance of the One Health concept by demonstrating the potential for Lactobacillales, commonly used in food products, to serve as reservoirs and vectors for ARGs.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk antimicrobial resistance genes iMGE Lactobacillales one health plasmid
Megjelenés:	Frontiers in Microbiology. - 14 (2023), p. 1-8. -
További szerzők:	Laczkó Levente (1992-) (biológus) Kardos Gábor (1974-) (szakorvos, klinikai mikrobiológus) Bányai Krisztián (virológus)
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