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001-es BibID:	BIBFORM118467
035-os BibID:	(scopus)85184558879 (wos)001157742800001
Első szerző:	Kenyeres Anna
Cím:	Age and lymphocyte/monocyte ratio as prognostic factors for autologous transplantation in the treatment of patients with follicular lymphoma / Kenyeres Anna, Kiss Evelin, Simon Zsófia, Illés Árpád, Jóna Ádám
Dátum:	2024
ISSN:	0300-0605
Megjegyzések:	Objective: Follicular lymphoma (FL) is an indolent, lymphoproliferative disease of B-cell origin that has a heterogeneous disease course with varying outcomes. Certain patients may undergo autologous stem cell transplantation. We investigated the outcome of autologous stem cell transplantation in patients with FL. Methods: Patients who received autologous stem cell transplantation at the University of Debrecen's Department of Hematology between 2004 and 2021 were retrospectively analyzed. The overall survival (OS) and progression-free survival (PFS) after transplantation of patients with FL were examined. Prognostic factors that may influence the course of the disease were chosen. Results: Data were collected from 49 patients. OS was influenced only by age, whereas PFS was affected by age and the lymphocyte/monocyte ratio. The combination of age and lymphocyte/ monocyte ratio defined a patient population with a particularly unfavorable prognostic risk profile: patients over 47 years of age with a pre-transplant lymphocyte/monocyte ratio greater than or equal to 2.675. Conclusion: Age and lymphocyte/monocyte ratio were identified as useful prognostic factors for PFS in patients with FL following autologous stem cell transplantation.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Follicular lymphoma autologous hematopoietic stem cell transplantation lymphocyte/monocyte ratio age prognostic marker overall survival progression-free survival
Megjelenés:	Journal of International Medical Research. - 52 : 2 (2024), p. 1-10. -
További szerzők:	Kiss Evelin Simon Zsófia (1977-) (belgyógyász, haematológus) Illés Árpád (1959-) (belgyógyász, haematológus, onkológus) Jóna Ádám (1985-) (belgyógyász, hematológus)
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