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001-es BibID:	BIBFORM119954
035-os BibID:	(cikkazonosító)7545 (Scopus)85188889056 (WoS)001195576900036
Első szerző:	Nagy Nikoletta Andrea (biológus)
Cím:	The updated genome of the Hungarian population of Aedes koreicus / Nikoletta Andrea Nagy, Gábor Endre Tóth, Kornélia Kurucz, Gábor Kemenesi, Levente Laczkó
Dátum:	2024
ISSN:	2045-2322
Megjegyzések:	Vector-borne diseases pose a potential risk to human and animal welfare, and understanding their spread requires genomic resources. The mosquito Aedes koreicus is an emerging vector that has been introduced into Europe more than 15 years ago but only a low quality, fragmented genome was available. In this study, we carried out additional sequencing and assembled and characterized the genome of the species to provide a background for understanding its evolution and biology. The updated genome was 1.1Gbp long and consisted of 6099 contigs with an N50 value of 329,610 bp and a BUSCO score of 84%. We identifed 22,580 genes that could be functionally annotated and paid particular attention to the identifcation of potential insecticide resistance genes. The assessment of the orthology of the genes indicates a high turnover at the terminal branches of the species tree of mosquitoes with complete genomes, which could contribute to the adaptation and evolutionary success of the species. These results could form the basis for numerous downstream analyzes to develop targets for the control of mosquito populations.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Aedes Invasive mosquito Genome assembly Tird generation sequencing Hybrid assembly Functional annotation
Megjelenés:	Scientific Reports. - 14 : 1 (2024), p.1-12. -
További szerzők:	Tóth Gábor Endre Kurucz Kornélia Kemenesi Gábor Laczkó Levente (1992-) (biológus)
Pályázati támogatás:	PD142602 OTKA FK-138563 Egyéb RRF-2.3.1-21-2022-00010 Egyéb
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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