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001-es BibID:	BIBFORM120848
035-os BibID:	(Scopus)85125157188 (WOS)000759398100001
Első szerző:	Trujillo, Nancy
Cím:	Lack of age-related mosaic loss of W chromosome in long-lived birds / Nancy Trujillo, Mónica Martínez-Pacheco, Cecilia Soldatini, Sergio Ancona, Rebecca C. Young, Yuri V. Albores-Barajas, Alberto H. Orta, Cristina Rodríguez, Tamas Székely, Hugh Drummond, Araxi O. Urrutia, Diego Cortez
Dátum:	2022
ISSN:	1744-957X
Megjegyzések:	Females and males often exhibit different survival in nature, and it has been hypothesized that sex chromosomes may play a role in driving differential survival rates. For instance, the Y chromosome in mammals and the W chromosome in birds are often degenerated, with reduced numbers of genes, and loss of the Y chromosome in old men is associated with shorter life expectancy. However, mosaic loss of sex chromosomes has not been investigated in any non-human species. Here, we tested whether mosaic loss of theWchromosome (LOW) occurs with ageing in wild birds as a natural consequence of cellular senescence. Using loci-specific PCR and a target sequencing approach we estimated LOW in both young and adult individuals of two long-lived bird species and showed that the copy number of W chromosomes remains constant across age groups. Our results suggest that LOW is not a consequence of cellular ageing in birds. We concluded that the inheritance of theWchromosome in birds, unlike the Y chromosome in mammals, is more stable.
Tárgyszavak:	Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Ageing Fregata magnificens mosaic loss of chromosome W Sula nebouxii
Megjelenés:	Biology Letters. - 18 : 2 (2022), p. 1-6. -
További szerzők:	Martínez-Pacheco, Mónica Soldatini, Cecilia Ancona, Sergio Young, Rebecca C. Albores-Barajas, Yuri V. Orta, Alberto H. Rodríguez, Cristina Székely Tamás (1959-) (biológus) Drummond, Hugh Urrutia, Araxi Cortez, Diego
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