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001-es BibID:	BIBFORM121018
035-os BibID:	(Scopus)85191735329
Első szerző:	Otsokolhich, Marko
Cím:	SIOPE and ESOP recommendations for extemporaneous compounding of oral liquid medicine formulations in paediatric oncology / Marko Otsokolhich, Maxime Annereau, Tiene Bauters, Laszlo Horvath, Chahinez Nehal, Sherif Kamal, Gilles Vassal, Svetlana Buraja
Dátum:	2024
ISSN:	2772-610X
Megjegyzések:	Introduction Scarcity of age appropriate formulations for orally administered medicines for paediatric malignancies is a critical and ongoing issue which necessitates urgent solutions. According to JARC Survey 27?% of oral medicines were never available in child-friendly formulations (Vassal et al., 2021 [2]). Pharmacists from the European Society of Oncology Pharmacy Global (ESOP) and the European Society for Pediatric Oncology (SIOPE) have collaborated to provide a document summarising literature data on this topic and a set of practical instructions on the preparation of extemporaneous oral liquid medicines. Material and methods Literature review was conducted for the preparation of oral medicines for paediatric cancer, through Pubmed 2.0. A table was drawn up with necessary information for medicine preparation. We adapted the classification model of the molecule stability ranking of the International database of stability for injectable drugs, Stabilis? (Class A?C). Results A total of 126 articles were selected and analysed. All commercially available marketed liquid oral medications used in paediatric cancer were overviewed using globally accessible drug databases and compiled in a table with appropriate indications. Based on the literature review, 28 formulations for 13 different active ingredients for chemotherapy and 35 formulations for 16 different active ingredients for supportive therapy were compiled. Conclusions Development of child-appropriate formulations of anticancer medicines by the pharmaceutical industry should be incentivised towards marketing authorisation to enhance accessibility. The results of this study could help facilitate creation of European standards for extemporaneous preparation and persuade researchers in the field of paediatric oncology on the way forward.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Paediatric oncology Pharmacy Extemporaneous preparation Compounding Age appropriate medicine formulations
Megjelenés:	EJC Paediatric Oncology. - 3 (2024), p. 1-7. -
További szerzők:	Annereau, Maxime Bauters, Tiene Horváth László (1973-) (gyógyszerész) Nehal, Chahinez Kamal, Sherif Vassal, Gilles Buraja, Svetlana
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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