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001-es BibID:BIBFORM121827
035-os BibID:(WOS)000998947700010
Első szerző:Apeksha Reddy, Pulliahgaru
Cím:Navigating the Complexities of Intraventricular Hemorrhage in Preterm Infants : an Updated Review / Pulliahgaru Apeksha Reddy, Himabindu Sreenivasulu, Mohammad Shokrolahi, Sudheer Kumar Muppalla, Nurlan Abdilov, Rajasekar Ramar, Raghu Halappa Nagaraj, Sravya Vuppalapati
Dátum:2023
ISSN:2168-8184
Megjegyzések:Intraventricular hemorrhage (IVH) is a type of bleeding that occurs in the ventricular cavity of the brain. In this comprehensive study, we provide a summary of the pathogenesis, diagnosis, and treatment of intraventricular hemorrhage in premature infants. Preterm babies are at high risk of developing IVH because their germinal matrix is not fully developed, making their blood vessels more prone to rupture. However, that is not necessarily the case in all preterm babies as the inherent structure of the germinal matrix makes it more susceptible to hemorrhage. Incidences of IVH are discussed based on recent data which states that around 12,000 premature infants in the United States experience IVH each year. Although grades I and II make up the majority of IVH cases and are frequently asymptomatic, IVH remains a significant issue for premature infants in neonatal intensive care facilities worldwide. Grades I and II have been linked to mutations in the type IV procollagen gene, COL4A1, as well as prothrombin G20210A and factor V Leiden mutations. Intraventricular hemorrhage can be detected using brain imaging in the first seven to 14 days following delivery. This review also shines a light on reliable methods for identifying IVH in premature newborns like cranial ultrasound and magnetic resonance imaging along with the treatment of IVH which is primarily supportive and involves the management of intracranial pressure, the correction of coagulation abnormalities, and the prevention of seizures.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
intraventricular hemorrhage
microcirculation
cognitive impairment
phenobarbital
drift
neurosurgery
neurological
germinal matrix
neonatalpreterm infants
Megjelenés:Cureus Journal of Medical Science. - 15 : 5 (2023), p. 1-6. -
További szerzők:Sreenivasulu, Himabindu Shokrolahi, Mohammad Muppalla, Sudheer Kumar Abdilov, Nurlan Ramar, Rajasekar Halappa Nagaraj, Raghu Vuppalapati, Sravya
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