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001-es BibID:	BIBFORM123762
Első szerző:	Szegedi Andrea (bőrgyógyász)
Cím:	Drug Hypersensitivity Reactions / Szegedi Andrea, Remenyik Éva, Gellén Emese
Dátum:	2023
Megjegyzések:	Adverse drug reactions (ADR) are divided into two main groups, type A and type B reactions. Type A reactions represent nearly 80-85% of ADRs, are caused by predictable pharmacological actions of the drug and may occur in every individual. While type B reactions develop on the basis of individual predisposition. Type B reactions include hypersensitivity reactions, which cover allergic-immune reactions, pharmacological interaction with immune receptors (p-i concept) and pseudoallergy. Allergic-immune reactions and p-i concept are the immune-mediated drug hypersensitivity reactions, which can be type I, II, III and IV. Pseudoallergic reactions are non-immune-mediated, but usually imitate IgE mediated reactions with wheal and oedema formation. Drugs, or even the same drug can elicit drug hypersensitivity reactions via various mechanisms. The most common and severe forms of drug hypersensitivity reactions are urticaria, angioedema and anaphylaxis, maculopapular drug eruption (MDE), acute generalized exanthematous pustulosis (AGEP), drug reaction with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). For correct diagnosis, detailed medical history is important and different test types are recommended, according to immediate or delayed type reactions.
ISBN:	978-3-031-15129-3
Tárgyszavak:	Orvostudományok Klinikai orvostudományok könyvfejezet könyvrészlet immune-mediated hypersensitivity pseudoallergy urticaria anaphylaxis toxic epidermal necrolysis
Megjelenés:	European Handbook of Dermatological Treatments / eds. Andreas D. Katsambas, Torello M. Lotti, Clio Dessinioti, Angelo Massimiliano D'Erme. - p. 229-245. -
További szerzők:	Remenyik Éva (1956-) (bőrgyógyász) Gellén Emese (1986-) (bőrgyógyász)
Internet cím:	Szerző által megadott URL Intézményi repozitóriumban (DEA) tárolt változat DOI
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