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001-es BibID:	BIBFORM124435
035-os BibID:	(Scopus)85140065608 (WOS)001049662600004
Első szerző:	Praag, Dominique L. G. Van
Cím:	Neurocognitive correlates of probable posttraumatic stress disorder following traumatic brain injury / Dominique L. G. Van Praag, Kristien Wouters, Filip Van Den Eede, Lindsay Wilson, Andrew I. R. Maas, CENTER-TBI investigators and participants
Dátum:	2022
ISSN:	2772-5294
Megjegyzések:	Introduction Neurocognitive problems associated with posttraumatic stress disorder (PTSD) can interact with impairment resulting from traumatic brain injury (TBI). Research question We aimed to identify neurocognitive problems associated with probable PTSD following TBI in a civilian sample. Material and methods The study is part of the CENTER-TBI project (Collaborative European Neurotrauma Effectiveness Research) that aims to better characterize TBI. For this cross-sectional study, we included patients of all severities aged over 15, and a Glasgow Outcome Score Extended (GOSE) above 3. Participants were assessed at six months post-injury on the PTSD Checklist-5 (PCL-5), the Trail Making Test (TMT), the Rey Auditory Verbal Learning Test (RAVLT) and the Cambridge Neuropsychological Test Automated Battery (CANTAB). Primary analysis was a complete case analysis. Regression analyses were performed to investigate the association between the PCL-5 and cognition. Results Of the 1134 participants included in the complete case analysis, 13.5% screened positive for PTSD. Probable PTSD was significantly associated with higher TMT-(B-A) (OR ?= ?1.35, 95% CI: 1.14?1.60, p ?< ?.001) and lower RAVLT-delayed recall scores (OR ?= ?0.74, 95% CI: 0.61?0.91, p ?= ?.004) after controlling for age, sex, psychiatric history, baseline Glasgow Coma Scale and education. Discussion and conclusion Poorer performance on cognitive tests assessing task switching and, to a lesser extent, delayed verbal recall is associated with probable PTSD in civilians who have suffered TBI.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény hazai lapban folyóiratcikk Cognition Head injury Neuropsychology Posttraumatic stress disorder Stress
Megjelenés:	Brain and Spine. - 2 (2022), p. 1-11. -
További szerzők:	Wouters, Kristien Eede, Filip Van Den Wilson, Lindsay Maas, Andrew I. R. Sándor János (1966-) (orvos-epidemiológus) CENTER-TBI Participants and Investigators
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