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001-es BibID:BIBFORM124437
Első szerző:Rai, Mahendra
Cím:Assessing the efficacy of carbon nanodots derived from curcumin on infectious diseases / Mahendra Rai, Avinash P. Ingle, Gréta Törős, József Prokisch
Dátum:2024
ISSN:1478-7210 1744-8336
Megjegyzések:Introduction The threat of new, emerging, and multidrug-resistant microbes is increasing which has created the necessity for new antimicrobials. In this regard, nanotechnology can be an alternative for the treatment of infectious microbes. Curcumin has been used since ancient times as antimicrobials; however, it has limitations due to its less aqueous solubility, bioavailability, and biocompatibility. This problem can be solved by curcumin-derived carbon nanodots which are emerging antimicrobials of <10?nm size, water-soluble, biocompatible, less toxic, and fluorescent. Area covered The review discusses the application of curcumin-derived carbon nanodots against various pathogenic microbes including bacteria and dreaded viruses like SARS-CoV-2. In addition, the role of curcumin carbon nanodots in biolabelling of pathogenic microbes, mechanism of action, bioimaging, and therapy has been critically examined. Expert opinion Carbon nanodots play an important role in combating pathogenic microbes by early diagnosis, bioimaging, nanocarrier for antimicrobial drugs, and therapy of infectious diseases. Curcumin carbon nanodots have already demonstrated their benefits of being water soluble, bioavailable, and biocompatible. However, more thorough research is needed to understand the efficacy and safety of curcumin carbon nanodots. In the future, curcumin-derived carbon nanodots can be used as alternative antimicrobial agents to fight microbial infections including multidrug-resistant microbes.
Tárgyszavak:Természettudományok Kémiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
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Megjelenés:Expert Review of Anti-Infective Therapy. - "Accepted by Publisher" (2024). -
További szerzők:Avinash P. Ingle Törős Gréta (1991-) (tanszéki mérnök/élelmiszerbiztonsági- és minőségi mérnök) Prokisch József (1966-) (vegyész)
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