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001-es BibID:
BIBFORM125552
Cím:
Mathematical analysis with control of liver cirrhosis causing from HBV by taking early detection measures and chemotherapy treatment / Aqeel Ahmad, Muhammad Ali, Ali Hasan Ali, Magda Abd El-Rahman, Evren Hincal, Husam A. Neamah
Dátum:
2024
ISSN:
2045-2322
Megjegyzések:
Reformulating the physical processes associated with the evolution of di erent ailments in accordance with globally shared objectives is crucial for deeper comprehension. This study aims to investigate the mechanism by which the HB virus induces harmful in ammation of the liver, with a focus on early detection and therapy using corticosteroids or chemotherapy. Based on the developed hypothesis, a new mathematical model has been created for this purpose. The recently developed system for HBV is SEI1I2R, which is examined both quantitatively and qualitatively to determine its actual e ect on stability. Reliable conclusions are ensured by examining the system's boundedness, positivity, existence, uniqueness, and conducting local and global stability analysis all crucial components of epidemic models. Global stability is tested using Lyapunov rst derivative functions to assess the overall impact of asymptomatic persons and chemotherapy treatment. Additionally, the Lipschitz condition is used to con rm the unique solutions for the newly built HBV model using methods from xed point theory, thus meeting the requirements for uniqueness and existence. Since the population must maintain this property, positivity is con rmed using global derivatives and Lipschitz criteria to calculate the rate of change in each sub-compartment. Applying the Mittag-Le er kernel with a fractal-fractional operator to continuously monitor the HBV virus for liver cirrhosis infection yields dependable results. Furthermore, the current situation regarding the HBV outbreak pertaining to liver cirrhosis infection, along with the control measures implemented following early diagnosis through asymptomatic measures and chemotherapy treatment under constant observation, are established to prevent chronic stage infections. Simulations have been used to study the true behavior and impact of HBV in asymptomatic persons receiving chemotherapy for liver cirrhosis infection in the community. This research is essential for understanding the spread of viruses and developing control strategies based on our validated ndings to mitigate the risk factors associated with liver cirrhosis.
Tárgyszavak:
Természettudományok
Matematika- és számítástudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Hepatitis B model
Asymptomatic measures
Mittag-Le er kernel
Positive invariant region
Liver cirrhosis
Megjelenés:
Scientific Reports. - "Accepted by Publisher" : - (2024), p. 1-24. -
További szerzők:
Ahmad, Aqeel
Ali, Muhammad
Ali, Hasan Ali
Abd El-Rahman, Magda
Hincal, Evren
Neamah, Husam A. (1990-) (mérnök)
Internet cím:
Intézményi repozitóriumban (DEA) tárolt változat
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