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001-es BibID:	BIBFORM125697
Első szerző:	Takács Péter (szülész-nőgyógyász)
Cím:	Biomechanical Integrity Score of the Female Pelvic Floor for Stress Urinary Incontinence / Takacs Péter, Rátonyi Dávid, Koroknai Erzsébet, Pákozdy Krisztina, Sipos Attila Gergely, Van Raalte Heather, Lucente Vincent, Egorov Vladimir, Krasznai Zoárd Tibor, Kozma Bence
Dátum:	2024
ISSN:	0937-3462
Megjegyzések:	Introduction: Urinary incontinence (UI) is a prevalent condition, affecting more than 1 in 3 women at some point in their lives. Stress urinary incontinence (SUI) occurs when unintended urine leakage occurs during coughing, sneezing, or physical exertion. SUI is the most common type overall. Even though UI is widespread, it often goes unnoticed and unreported, with fewer than 40% of affected women seeking medical attention for this issue. It is, therefore, important for healthcare providers to accurately screen for and diagnose SUI. The Vaginal Tactile Imager (VTI) was developed to provide a biomechanical mapping of the pelvic floor with a vaginal probe. A set of new clinical markers/parameters has been proposed for the biomechanical characterization of pelvic floor conditions. This set included 52 parameters automatically calculated as a result of completing eight examination procedures (tests). Biomechanical Integrity score (BI-score) for pelvic organ prolapse (POP) was proposed. In order to make biomechanical mapping in urogynecology more accessible and valuable, further work is required on developing a shorter list of easily understandable and practical biomechanical parameters for SUI characterization. Objective: This study aims to develop and validate a new integral parameter, the BI-score of the female pelvic floor for SUI conditions. Methods: A total of 130 subjects with normal and SUI conditions were included in the observational cohort study; 70 subjects had normal pelvic floor conditions, and 60 subjects had SUI. VTI was used to acquire and automatically calculate 52 biomechanical parameters for eight VTI test procedures (probe insertion, elevation, rotation, Valsalva maneuver, voluntary muscle contractions in two planes, relaxation, and reflex contraction). Statistical methods were applied (t-test, correlation) to identify the VTI parameters sensitive to the pelvic SUI conditions. Results: 27 parameters were identified as statistically sensitive to the SUI development. They were subdivided into five groups to characterize (1) tissue elasticity, (2) pelvic support, (3) pelvic muscle contraction, (4) involuntary muscle relaxation, and (5) pelvic muscle mobility. Every parameter was transformed to its standard deviation units using the dataset for normal pelvic conditions, similar to the T-score for bone density. Linear combinations with specified weights led to the composition of five component parameters for groups (1)-(5) and to the BI-score in standard deviation units. The p-value for the BI-score has p=4.0?10-28 for SUI versus normal conditions. Conclusions: Based on the analysis conveyed, five components are vital for biomechanical characterizing the pelvic floor. All these components contribute to the integral parameter of the BI-score. Objectively measurable transformations of the pelvic tissues, support structures, and functions under different diseased conditions may be studied with the BI-score in future research and practical applications.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idézhető absztrakt folyóiratcikk
Megjelenés:	International Urogynecology Journal. - 35 : Suppl. 1 (2024), p. S208-S209. -
További szerzők:	Rátonyi Dávid (1996-) (Szülész-nőgyógyász) Koroknai Erzsébet (1987-) (szülész-nőgyógyász) Pákozdy Krisztina (1991-) (szülész-nőgyógyász) Sipos Attila Gergely (1990-) (szülész-nőgyógyász) van Raalte, Heather Lucente, Vincent Egorov, Vladimir Krasznai Zoárd Tibor (1973-) (szülész-nőgyógyász, gyermeknőgyógyász) Kozma Bence (1982-) (szülész-nőgyógyász)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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