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001-es BibID:	BIBFORM125947
Első szerző:	Lovas Szabolcs (tudományos segédmunkatárs)
Cím:	Primary prevention of type 2 diabetes in the EU : a systematic review of interventional studies / Lovas S., Soares Andrade C. A., Mahrouseh N., Chamouni G., Shahin B., Wangeshi Njuguna D., Israel F., Awad Mustafa Eltayeb O., Aisul Muhlis A. N., Varga O.
Dátum:	2024
ISSN:	1101-1262
Megjegyzések:	Background The GBD 2019 study revealed that type 2 diabetes caused over 109.000 deaths and accounted for 5.3 million Disability Adjusted Life Years in the EU, with an estimated annual cost of EUR 300 billion in 2014. Interventions for primary prevention are pivotal in preventing diabetes, providing a structured approach to implementing lifestyle modifications or community-based programs. The objective of this study was to demonstrate the effectiveness of primary prevention interventions to prevent or delay the onset of type 2 diabetes in the EU member states. Methods A systematic review on six databases was conducted for relevant interventional studies carried out in the EU-28. The main outcome of the studies was determined by changes in the incidence of type 2 diabetes. Results The search yielded 18.885 records, of which 18 met the eligibility criteria. The following studies reported significant incidence reduction in the intervention groups: The Finnish Diabetes Prevention Study by individualised lifestyle intervention (HR: 0.614, 95%CI: 0.478-0.789), the Spanish CORDIOPREV Study through increased plant protein intake (HR: 0.64, 95%CI: 0.43-0.96), the Spanish PreDE trial by promoting healthy diet and physical exercise (RR: 0.68, 95%CI: 0.47-0.99), the Norfolk Diabetes Prevention Study with intensive diet-exercise counselling (OR: 0.57, 95%CI: 0.38-0.87), the Spanish PREDIMED and PREDIMED-Reus trials by mediterranean diet supplemented with extra virgin olive oil or mixed nuts (HR: 0.60, 95%CI: 0.43-0.85; HR: 0.49, 95%CI: 0.25-0.97; HR: 0.48, 95%CI: 0.24-0.96), and the Dutch SLIM Study with advices on diet and physical activity (RR: 0.53, 95%CI: 0.29-0.97). Conclusions Significantly decreasing the incidence of diabetes is feasible within primary healthcare settings through intensive lifestyle interventions targeting individuals at high risk. Therefore, it would be beneficial to incorporate these findings into the European guidelines for preventing type 2 diabetes. Key messages Primary care plays an important role in the prevention of type 2 diabetes. Well-defined primary lifestyle interventions are capable of slowing the progression from prediabetes to diabetes.
Tárgyszavak:	Orvostudományok Egészségtudományok idézhető absztrakt folyóiratcikk
Megjelenés:	European Journal Of Public Health. - 34 : Supplement 3 (2024), p. 500. -
További szerzők:	Soares Andrade, Carlos Alexandre (1993-) (PhD hallgató) Mahrouseh, Nour (1993-) (Phd hallgató) Chamouni, G. Shahin, Balqees Wangeshi Njuguna, Diana Israel, Frederico Epalanga Albano (1991-) (PhD hallgató) Awad Mustafa Eltayeb, O. Aisul Muhlis, A. N. Varga Orsolya (1977-) (orvos, jogász)
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