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001-es BibID:	BIBFORM005627
Első szerző:	Danicek, Vladimir
Cím:	Sinus rhythm restoration after atrial fibrillation : the clinical value of N-terminal pro-BNP measurements / Danicek, V., Theodorovich, N., Bar-Chaim, S., Miller, A., Vered, Z., Koren-Morag, N., Uriel, N., Czuriga, I., Shopen, A., Brantriss, N., Kaluski, E.
Dátum:	2008
ISSN:	1540-8159 (Electronic)
Megjegyzések:	To examine the effects of sinus rhythm (SR) restoration on N-Terminal pro-BNP (NTP-BNP) in patients with atrial fibrillation (AF). METHODS: Subjects with paroxysmal and persistent AF and absence of organic heart disease were prospectively studied. Chemical or electrical restoration of SR was attempted within 48 hours (n = 37) or >3 weeks (n = 73). Clinical and laboratory (NTP-BNP, 72-hour Holter monitor, and electrocardiogram) assessment were obtained at baseline and at 1, 30, and 180 days after SR restoration. Patients were divided into three predefined "outcome groups": (a) maintenance of SR for 1 month, (b) SR with recurrent paroxysmal AF (PaAF), and (c) early (<30 days) recurrence persistent AF (RAF). RESULTS: Of the 110 patients enrolled, 89 had initial successful SR restoration. Baseline NTP-BNP was 936 pg/mL (interquartile range (IQR) 333-2,026); ratio between baseline and 30-day NTP-BNP was 10.2 (IQR 6.42-22.0) for SR group, 3.3 (IQR 2.45-7.34) for PaAF, and 1.07 (IQR 0.87-1.22) for RAF (P < 0.001). Patients with ratio </=3 were more likely to have PaAF (46% vs 3%, OR 30, P < 0.001). CONCLUSION: With SR restoration, NTP-BNP decline is observed up to 1 month. NTP-BNP drop is partially or completely abolished by PaAF and RAF, respectively. NTP-BNP does not predict successful SR restoration.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Aged Atrial Fibrillation Female Humans Male Middle Aged Natriuretic Peptide, Brain Outcome Assessment (Health Care) Peptide Fragments Prognosis Recovery of Function Reproducibility of Results Risk Assessment Risk Factors Sensitivity and Specificity Treatment Outcome
Megjelenés:	Pacing and Clinical Electrophysiology. - 31 : 8 (2008), p. 955-960. -
További szerzők:	Theodorovich, Nick Bar-Chaim, Shmuel Miller, Asaf Vered, Zvi Koren-Morag, Nira Uriel, Nir Czuriga István (1948-2018) (kardiológus) Shopen, Andrey Brantriss, Nurit Kaluski, Edo
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