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001-es BibID:BIBFORM005995
Első szerző:Surányi Péter
Cím:Modulation of T3 antigen in systemic lupus erythematosus (SLE) / Suranyi, P., Czirják, L., Szegedi, G., Damjanovich, S.
Dátum:1987
Megjegyzések:One of the first steps in the T cell activation is modulation of T3-Ti complex from the cell membrane. This process was studied in patients with SLE by immunofluorescence staining and measured in a cell sorter. The modulation of T3 antigen was impaired in a number of patients. The mitogen-induced proliferation was also decreased in these cases, but decreased blast transformation occurred also with efficient modulation. Pretreatment of normal T lymphocyte with sera from patients with decreased modulation caused only moderate inhibition of T3 antigen modulation. Modulation in vitro was not influenced by steroids.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény hazai lapban
Antibodies,Monoclonal
Antigens,CD3
Antigens,Differentiation,T-Lymphocyte
Binding Sites
Binding Sites,Antibody
Cell Membrane
Cells,Cultured
drug effects
Flow Cytometry
Human
Hungary
Hydrocortisone
immunology
In Vitro
Lupus Erythematosus,Systemic
Lymphocyte Transformation
pharmacology
T-Lymphocytes
Megjelenés:Acta Medica Hungarica. - 44 : 4 (1987), p. 311-319. -
További szerzők:Czirják László Szegedi Gyula (1936-2013) (belgyógyász, immunológus) Damjanovich Sándor (1936-2017) (biofizikus)
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