Összesen 1 találat.
#/oldal:
Részletezés:
Rendezés:

1.

001-es BibID:BIBFORM007151
Első szerző:Veres Katalin (orvos)
Cím:Antiphospholipid antibodies in acute coronary syndrome / Veres, K., Lakos, G., Kerenyi, A., Szekanecz, Z., Szegedi, G., Shoenfeld, Y., Soltesz, P.
Dátum:2004
ISSN:0961-2033 (Print)
Megjegyzések:Antiphospholipid (aPL) antibodies entailing anticardiolipin (aCL) and anti-beta2 glycoprotein I (anti-beta2GPI) antibodies may be involved in a number of vascular diseases including coronary artery diseases (CAD) or stroke. Here we assessed the presence of aPL antibodies in acute coronary syndrome (ACS). The frequency of anti-beta2GPI antibodies was significantly higher (14.4%) in ACS in comparison to control healthy subjects (2%). In addition, serum concentrations of anti-beta2GPI antibodies were also increased in ACS. Anti-beta2GPI antibodies of the IgA isotype might be the most relevant for the onset and outcome of ACS. Regarding subclasses of ACS, anti-beta2GPI IgA antibodies were elevated in unstable angina (UA) and myocardial infarction with ST elevation (STEMI), but not in myocardial infarction without ST elevation (NSTEMI). The involvement of anti-beta2GPI antibodies in ACS was more pronounced in men than women, and in younger rather than older patients. Finally, anti-beta2GPI antibodies in ACS were associated with previous stroke, but not with hypertension or previous myocardial infarction. Thus, anti-beta2GPI antibodies may be involved in the thrombotic events underlying ACS.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Adult
Aged
Aged, 80 and over
Antibodies, Anticardiolipin
Antibodies, Antiphospholipid
Enzyme-Linked Immunosorbent Assay
Female
Glycoproteins
Humans
Lupus Coagulation Inhibitor
Male
Middle Aged
Myocardial Infarction
Risk Factors
beta 2-Glycoprotein I
Megjelenés:Lupus. - 13 : 6 (2004), p. 423-427. -
További szerzők:Lakos Gabriella (1963-) (laboratóriumi szakorvos, transzfúziológus, immunológus) Kerényi Adrienne (1970-) (laboratóriumi szakorvos) Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Szegedi Gyula (1936-2013) (belgyógyász, immunológus) Shoenfeld, Yehuda Soltész Pál (1961-) (belgyógyász, kardiológus)
Internet cím:elektronikus változat
elektronikus változat
DOI
Borító:
Rekordok letöltése1