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001-es BibID:BIBFORM009114
Első szerző:Rusznák Zoltán (élettanász)
Cím:Spiral ganglion neurones : an overview of morphology, firing behaviour, ionic channels and function / Zoltán Rusznák, Géza Szűcs
Dátum:2009
ISSN:0031-6768
Megjegyzések:The spiral ganglion cells provide the afferent innervation of the hair cells of the organ of Corti. Ninety-five percent of these cells (termed type I spiral ganglion neurones) are in synaptic contact with the inner hair cells, whereas about 5% of them are type II cells, which are responsible for the sensory innervation of the outer hair cells. To understand the function of the spiral ganglion neurones, it is important to explore their membrane properties, understand their activity patterns and describe the variety of ionic channels determining their behaviour. In this review, a brief description is given of the various experimental methods that allow the investigation of the spiral ganglion cells, followed by the discussion of their action potential firing patterns and ionic conductances. The presence, distribution and significance of the K(+) currents of the spiral ganglion cells are specifically addressed, along with the introduction of the putative subunit compositions of the relevant voltage-gated K(+) channels
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
action potentials
Aging
anatomy and histology
Animals
behaviour
Brain-Derived Neurotrophic Factor
calcium
calcium channel
Cells,Cultured
channel
cytology
drug effects
Elapid Venoms
Hair Cells
Health
Histological Techniques
Humans
innervation
metabolism
method
morphology
mouse
nerve
Nerve Growth Factors
neurone
Neurons
Organ of Corti
pharmacology
physiology
Potassium
potassium channel
review
Sodium
sodium channel
Spiral Ganglion
Megjelenés:Pflügers Archiv. - 457 : 6 (2009), p. 1303-1325. -
További szerzők:Szűcs Géza (1948-) (élettanász)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
DOI
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