Találati lista | Tudóstér

001-es BibID:	BIBFORM015628
Első szerző:	Szöőr Árpád (orvos)
Cím:	Rafts and the battleships of defense : the multifaceted microdomains for positive and negative signals in immune cells / Szoor, A., Szollosi, J., Vereb, G.
Dátum:	2010
Megjegyzések:	Recognition of the heterogeneity of the cell membrane was one of the most important scientific achievements in the last decades. Since coining the term "lipid rafts", continuous development of advanced microscopic and spectroscopic techniques has vastly expanded our view on these cell membrane microdomains that appear to have almost as many faces as researchers that look at them; they are variable in stability, size and composition that can change in a highly dynamic manner both by recruiting and expelling components as well as by coalescing and breaking up into smaller units. They have, however, one common feature: all eukaryotic cells present some variation of lipid rafts. Cells of the immune system are not exception to this, regardless of their lymphoid or myeloid origin their membranes show a domain structure and these domains serve to condense or reject particular transmembrane, GPI-linked and intracellularly membrane-anchored proteins as function requires. Here we provide a concise overview about the various weapons and shields that immune cells concentrate into their rafts, which have come into sight during the past years. The positive and negative regulatory roles of these microdomains are essential both in the functions of innate immunity and processes concatenated in the adaptive immune response
Tárgyszavak:	Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban article Biophysics Cell Membrane Cells Eukaryotic Cells Hungary Immune System lipid raft Membrane Microdomains Proteins Research Research Support Support OTKA::1 MAB::3.1
Megjelenés:	Immunology Letters. - 130 : 1-2 (2010), p. 2-12. -
További szerzők:	Szöllősi János (1953-) (biofizikus) Vereb György (1965-) (biofizikus, orvos)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
Borító:
Saját polcon: