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001-es BibID:	BIBFORM016346
035-os BibID:	WOS:A1989U197300005 PMID:2751327
Első szerző:	Maródi László (gyermekgyógyász infektológus, immunológus)
Cím:	Opsonic activity in serum from septic infants treated with intravenous immunoglobulin / Maródi L., Kalmár A., Szabó I.
Dátum:	1989
Megjegyzések:	Thirteen infants with staphylococcal sepsis and reduced opsonic activity received infusions of acid treated immunoglobulin together with antibiotics. Opsonic activity (using Staphylococcus aureus (type 42D) as the test organism), haemolytic activity of complement, and concentrations of complement C3 and IgG were measured in serum prepared before and after three days of treatment with immunoglobulin at a dose of 250-300 mg/kg/day. There was increased ingestion of S aureus by normal human granulocytes in the presence of fresh serum prepared after infusion of immunoglobulin and significantly increased opsonic activity of heat inactivated serum after treatment with immunoglobulin. The haemolytic activity of complement and concentrations of complement C3 were not influenced, and serum concentrations of IgG increased as the result of receiving a total of 800-900 mg/kg immunoglobulin over a period of three days. This study shows that administration of acid treated IgG to septic infants leads to functionally increased opsonisation.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban egyetemen (Magyarországon) készült közlmény
Megjelenés:	Archives of Disease in Childhood. - 64 : 4 (1989), p. 530-534. -
További szerzők:	Kalmár Ágnes Szabó Imre (1952-) (orvos)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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