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001-es BibID:BIBFORM016933
035-os BibID:(WoS)A1996TM60000004 (Scopus)0029688481
Első szerző:Bogner Péter (radiológus)
Cím:Nuclear magnetic resonance relaxation parameters of muscle in malignant hyperthermia-susceptible swine / Péter Bogner, Ervin Berényi, Attila Miseta, Péter Horn, Miklós Kellermayer, Denys N. Wheatley, Ferenc A. Jolesz
Dátum:1996
ISSN:1076-6332
Megjegyzések:Rationale and Objectives. The malignant hyperthermia (MH) syndromeinvolves characteristic changes in metabolism that have a significanteffect on the postmortem properties of muscle tissue. We investigatedthe H-1 nuclear magnetic resonance (MR) relaxation parameters of muscletissue from normal (MH-) and malignant hyperthermia-susceptible (MH+)swine taken before their death to identify whether postmortem metabolicdifferences would be accompanied by changes in relaxation parameters.Methods. Muscle samples from 63 MH-susceptible swine were characterizedby proton MR relaxation times (T1 and T2). The water content, pH,conducting, and the ''subjective meat'' quality were assessed in orderto differentiate the meat into one of three groups: normal,pale-soft-exudative, and dark-firm-dry.Results. The T2 relaxation of MH- and MH+ muscles was significantlydifferent, but no significant changes were detected in the watercontent and corresponding T1 relaxation times.Conclusion. These data suggest that MH-susceptible swine can bedistinguished from normal swine using nuclear MR relaxometry. Theresults of relaxation measurements and the multiexponential analysis ofthe T2 curves suggest a shift between the different water compartmentsduring MH that might predict the increased water loss of muscle tissueafter death.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Academic Radiology. - 3 : 1 (1996), p. 26-30. -
További szerzők:Berényi Ervin (1964-) (radiológus) Miseta Attila Horn Péter Kellermayer Miklós Wheatley, Denys N. Jolesz Ferenc A.
Internet cím:DOI
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