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001-es BibID:	BIBFORM024302
Első szerző:	Barkai László (gyermekgyógyász)
Cím:	Physical work capacity in diabetic children and adolescents with and without cardiovascular autonomic dysfunction / L. Barkai, M. Peja, I. Vámosi
Dátum:	1996
Megjegyzések:	The aim of the present study was to evaluate the influence of autonomic nervous system dysfunction on work capacity in children and adolescents with Type 1 (insulin-dependent) diabetes. Fifteen patients with autonomic dysfunction (abnormal autonomic tests, age: 14.9?2.3 years), 35 patients without autonomic dysfunction (normal autonomic tests, age: 15.2?2.5 years), and 25 non-diabetic subjects (age: 15.0?2.3 years) were investigated. Resting heart rate, deep breathing heart rate variation, standing/lying heart rate ratio, decrease in blood pressure during orthostasis, and increase in blood pressure during sustained handgrip were used to assess cardiovascular autonomic dysfunction. Physical work capacity at heart rate of 170 min<sup>-1</sup> was determined by bicycle ergometry. Glycated haemoglobin level was higher in patients with than without autonomic dysfunction (12.3?3.1 vs 9.4?2.9%, p = 0.04). Patients with autonomic dysfunction had significantly lower physical work capacity at heart rate of 170 min<sup>-1</sup> than those with normal autonomic function or non-diabetic subjects (0.81?0.12 vs 1.49?0.16 and 1.54?0.20 W kg<sup>-1</sup> p = 0.01). Physical work capacity at heart rate of 170 min<sup>-1</sup> was related to glycated haemoglobin level (r = -0.55, p = 0.01), to resting heart rate (r = 0.57, p =0.01), and to deep breathing heart rate variation (r = 0.51, p 0.02). In conclusion, impaired work capacity is associated with poor blood glucose control and cardiovascular autonomic dysfunction. Autonomic tests can help to identify those patients who may need special consideration during exercise. PubMed ID: 8689847 UR: http://www.scopus.com/inward/record.url?eid=2-s2.0-0029969535&partnerID=40&md5=a04f51d2cacb00d6d7e8cf8b711e215a http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-0029969535
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Respiration Reference Values Posture Male Humans Heart Rate Female Exertion Exercise Test Electrocardiography Diabetic Angiopathies Diabetes Mellitus, Type 1 Confidence Intervals Child Blood Pressure Adolescent Work capacity school child major clinical study insulin dependent diabetes mellitus human diabetes control controlled study autonomic nervous system function autonomic dysfunction ARTICLE glycosylated hemoglobin diabetes mellitus CHILDREN Autonomic function Adolescents
Megjelenés:	Diabetic Medicine. - 13 : 3 (1996), p. 254-258. -
További szerzők:	Peja Márta Vámosi Ildikó
Internet cím:	DOI Intézményi repozitóriumban (DEA) tárolt változat
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