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001-es BibID:	BIBFORM032019
035-os BibID:	PMID:8159284 WOS:A1994MQ30200005
Első szerző:	Laczi Ferenc (Szeged)
Cím:	The role of central corticoliberin in the ether stress-induced secretion of neurohypophyseal hormones and corticosterone in the rat / F. Laczi, T. Ivanyi, Z. Sarnyai, M. Vecsernyes, G. Lengyel, G. Szabo, É. Biro, J. Gardi, J. Julesz, G. Telegdy
Dátum:	1994
Megjegyzések:	As corticotropin-releasing factor (CRF) and oxytocin (OXT) are released in response to various stressors and a role of CRF in stress-induced OXT secretion has been proposed by previous authors, the present experiments were scheduled to investigate the participation of the brain CRF system in the stress-evoked release of OXT, arginine-8-vasopressin (AVP) and corticosterone. CRF-antiserum (AS) was given into the lateral ventricle of the brain of Wistar male rats, and 24 h later, the injection was repeated 30 min prior to ether stress followed by decapitation in 5 min. Plasma OXT and AVP were measured by radioimmunoassay and corticosterone by fluorimetry. Ether stress increased the levels of corticosterone and OXT, but not that of AVP. CRF-AS alone did not change the secretion of these hormones. CRF-AS pretreatment blocked the corticosterone-releasing action of ether stress, whereas it exerted no influence on the stress-induced OXT secretion into the circulation. There was no effect of a combined application of CRF-AS and stress on the plasma AVP level. These results suggest that the central CRF system is involved in the ether stress-elicited corticosterone response, however CRF is unlikely to be connected with the regulation of OXT secretion under these experimental conditions.
Tárgyszavak:	Orvostudományok Gyógyszerészeti tudományok idegen nyelvű folyóiratközlemény külföldi lapban egyetemen (Magyarországon) készült közlemény
Megjelenés:	Neuropeptides 26 : 1 (1994), p. 33-37. -
További szerzők:	Iványi Tibor Sarnyai Zoltán Vecsernyés Miklós (1959-) (gyógyszertechnológus, endokrinológus) Lengyel Gabriella Szabó Gyula (Szeged) Bíró Éva Gardi János Julesz János Telegdy Gyula (Szeged)
Pályázati támogatás:	1350 OTKA
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
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