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001-es BibID:	BIBFORM034480
Első szerző:	Rák Kálmán (belgyógyász, klinikai hematológus, véralvadás kutató)
Cím:	Plasma levels of beta-thromboglobulin and factor VIII-related antigen in diabetic children and adults / K. Rak, P. Beck, M. Udvardy, G. Pfliegler, M. Misz, Z. Boda
Dátum:	1983
ISSN:	0049-3848
Megjegyzések:	In order to investigate the relationship between the in vivo platelet activation in diabetes mellitus and the endothelial damage connected with the diabetic micro- and/or macroangiopathy, plasma levels of beta-thromboglobulin (B-TG) and of factor VIII-related antigen (VIII R:Ag) were studied (1) in juvenile-onset (Type I) diabetics without clinical signs of angiopathy (age under 12 years) and (2) in mostly maturity-onset (Type II) diabetics with and without overt angiopathy (age between 14 and 60 years). Normal controls and nondiabetics with atherosclerosis were also studied. Plasma levels of both proteins were found to be elevated in all the groups of diabetic and atherosclerotic patients in comparison with the controls. Highest levels were found in adult diabetics with angiopathy and in atherosclerotics even without diabetes, but values of the diabetic children were also elevated. The data suggest a causal relationship between the vascular damage and the enhanced platelet reactivity in which the former may play the primary role.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban beta-thromboglobulin factor VIII-related antigen diabetes mellitus diabetic angiopathy atherosclerosis egyetemen (Magyarországon) készült közlemény
Megjelenés:	Thrombosis Research. - 29 : 2 (1983), p. 155-162. -
További szerzők:	Beck Piroska Udvardy Miklós (1947-) (belgyógyász, haematológus) Pfliegler György (1949-) (belgyógyász, hematológus, labor szakorvos) Misz Mária Boda Zoltán (1947-) (belgyógyász, haematologus, klinikai onkológus)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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