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001-es BibID:	BIBFORM042503
035-os BibID:	PMID:517047
Első szerző:	Balogh Ádám (szülész-nőgyógyász, endokrinológus szakorvos)
Cím:	Effect of the norethisterone minipill on the plasma levels of biologically and immunologically active luteinizing hormone in women / A. Balogh, D. M. Robertson, E. Diczfalusy
Dátum:	1979
Megjegyzések:	Daily levels of LH (luteinizing hormone) were measured in 29 healthy women and compared with in vitro bioassays and immunological assays (radioimmunoassay) to determine the effect of NET (norethisterone), administered as a low-dose formulation (.3 mg/day), on levels of biologically and immunologically active LH. Measurements of NET were made daily throughout the menstrual cycle in the women before and during the 2nd month of NET administration. All 29 control cycles showed the characteristic midcycle LH surge; however, only 10 treated cycles exhibited this surge; even in those cycles showing the LH surge, the level of LH was noticeable depressed (P.001) throughout the menstrual cycle. A biological-to-immunological ratio (B/I) was quantified, and among these 10 treatment cycles with LH surge, there was no difference of statistical significance in B/I between control and treatment cycles. In the 19 remaining cycles in which no midcycle LH peak occurred, both biological and immunological activities of LH were significantly reduced (P.05) compared with those in the follicular phase of controls and were significantly higher than in control luteal phase (P.05). For these 19 subjects, the B/I ratio was significantly lower in treatment periods than in control cycles (P.001); still, the article concludes that even during treatment with NET, both biological and immunological LH behave irregularly, but the irregular patterns are of similar kind.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban egyetemen (Magyarországon) készült közlemény
Megjelenés:	Acta Endocrinologica. - 92 : 3 (1979), p. 428-436. -
További szerzők:	Robertson, D. M. Diczfalusy, E.
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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