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001-es BibID:	BIBFORM062413
Első szerző:	Ebrahimi, Fatemeh
Cím:	Carriage Rates and Characteristics of Enterobacteriaceae Producing Extended-Spectrum Beta-Lactamases in Healthy Individuals : comparison of Applicants for Long-Term Care and Individuals Screened for Employment Purposes / Fatemeh Ebrahimi, Julianna Mózes, Júlia Mészáros, Ágnes Juhász, Gábor Kardos
Dátum:	2015
ISSN:	0009-3157
Megjegyzések:	AIMS:We compared the prevalence of extended-spectrum beta-lactamase (ESBL) producers in the faecal samples of 1,109 healthy individuals screened for employment purposes and in 531 asymptomatic individuals applying for long-term care (LTC).METHODS:Eosin-methylene blue agar plates supplemented with 2 mg/l cefotaxime were used to determine which individuals were ESBL producers. ESBL phenotype was confirmed by double-disk synergy test and ESBL genes were identified by sequencing. ESBL producers were characterized by co-resistance and integron carriage.RESULTS:ESBL producers were more frequent in the LTC applicants than in the employment screening individuals (7.2 vs. 2.0%; p < 0.0001), with 43 Escherichia coli, 18 Klebsiella pneumoniae, 1 Klebsiella oxytoca and 1 Proteus mirabilis being found. In the employment screening individuals, only E. coli was found. Most ESBL genes (79.4%, 50/63) were blaCTX-M type; blaCTX-M-15 was more frequent in the LTC applicants (p < 0.001). Regarding ESBL genes and integron diversity, E. coli isolates from the LTC applicants were more similar to K. pneumoniae than to E. coli from the employment screening individuals.CONCLUSION:These differences in the characteristics of ESBL producers may represent different sources of colonization. Most LTC applicants harboured K. pneumoniae or E. coli that were probably hospital-acquired whereas the E. coli isolates of many healthy individuals showed similarities to environmental E. coli.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Enterobacteriacea beta-lactamases E. coli Klebsiella
Megjelenés:	Chemotherapy. - 60 : 4 (2015), p. 239-249. -
További szerzők:	Mózes Julianna (1982-) (orvosdiagnosztikai laboratóriumi analitikus, okleveles népegészségügyi szakember) Mészáros Júlia Juhász Ágnes Kardos Gábor (1974-) (szakorvos, klinikai mikrobiológus)
Pályázati támogatás:	TÁMOP 4.2.4. A/2-11-1-2012-0001 TÁMOP
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