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001-es BibID:	BIBFORM064234
Első szerző:	Gelley Fanni
Cím:	Recurrence of primary sclerosing cholangitis after liver transplantation : the Hungarian experience / Fanni Gelley, Gergely Zádori, Dénes Görög, László Kóbori, Imre Fehérvári, György Gámán, Zsuzsanna Gerlei, Péter Nagy, Enikő Sárváry, Balázs Nemes
Dátum:	2014
Megjegyzések:	Introduction: Recurrence of primary sclerosing cholangitis (rPSC) after liver transplantation (OLT) signifi cantly aff ects longtermgraft survival. We aimed to evaluate the incidence of rPSC and clinical data of these patients in Hungary. Patients and Methods:We retrospectively analyzed data of 511 whole liver transplantations from 1995 to 2011. During the study period, 49 OLTs were performedin 43 adult patients with end-stage PSC (10%). Results: Out of 49 OLT, 24 cases were excluded, rPSC was diagnosed in six patients (12%).Patients with rPSC had signifi cantly higher mortality (p = 0.009) and graft loss (p = 0.009) in comparison to patients without recurrent disease.Younger recipient age, higher donor BMI was observed in the rPSC group. One patient was diagnosed with de novo IBD, the remaining fi vepatients had worsening IBD activity in the posttransplant period. PreOLT colectomy was performed in 21% of the control and none of therPSC group. PostOLT colectomy was performed in two rPSC patients due to severe therapy resistant colitis. Conclusions: Recurrent PSCsignifi cantly aff ects long-term mortality and graft loss. Younger age at OLT, higher donor BMI and severe active IBD may be associated withPSC recurrence. PreOLT total colectomy might have protective eff ect against rPSC.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény hazai lapban
Megjelenés:	Interventional Medicine & Applied Science 6 : 1 (2014), p. 16-18. -
További szerzők:	Zádori Gergely (1983-) (sebész) Görög Dénes Kóbori László Fehérvári Imre Gámán György Gerlei Zsuzsa Nagy Péter Sárváry Enikő Nemes Balázs Áron (1969-) (sebész)
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