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001-es BibID:	BIBFORM068575
Első szerző:	Chaoui, R.
Cím:	Maxillary gap at 11-13 weeks' gestation : marker of cleft lip and palate / Chaoui R., Orosz G., Heling K. S., Sarut-Lopez A., Nicolaides K. H.
Dátum:	2015
ISSN:	0960-7692
Megjegyzések:	ObjectiveTo describe a new sign of cleft lip and palate (CLP), the maxillary gap, which is visible in the mid-sagittal plane of the fetal face used routinely for measurement of nuchal translucency thickness.MethodsThis was a retrospective study of stored images of the mid-sagittal view of the fetal face at 11?13 weeks' gestation in 86 cases of CLP and 86 normal controls. The images were examined to determine if a maxillary gap was present, in which case its size was measured.ResultsIn 37 (43.0%) cases of CLP the defect was isolated and in 49 (57.0%) there were additional fetal defects. In the isolated CLP group, the diagnosis of facial cleft was made in the first trimester in nine (24.3%) cases and in the second trimester in 28 (75.7%). In the group with additional defects, the diagnosis of facial cleft was made in the first trimester in 46 (93.9%) cases and in the second trimester in three (6.1%). A maxillary gap was observed in 96% of cases of CLP with additional defects, in 65% of those with isolated CLP and in 7% of normal fetuses. There was a large gap (>1.5?mm) or complete absence of signals from the maxilla in the midline in 69% of cases of CLP with additional defects, in 35% of those with isolated CLP and in none of the normal controls.ConclusionsThe maxillary gap is a new simple marker of possible CLP, which could increase the detection rate of CLP, especially in isolated cases. Copyright ? 2015 ISUOG. Published by John Wiley & Sons Ltd.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Maxillary gap
Megjelenés:	Ultrasound In Obstetrics & Gynecology. - 46 : 6 (2015), p. 665-669. -
További szerzők:	Orosz Gergő Balázs (1985-) (szülész-nőgyógyász) Heling, K. S. Sarut-Lopez, A. Nicolaides, Kypros H.
Internet cím:	DOI Intézményi repozitóriumban (DEA) tárolt változat
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