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001-es BibID:BIBFORM073797
Első szerző:Bhatta, Anil Kumar
Cím:Vertical transmission of herpes simplex virus : an update / Bhatta Anil Kumar, Keyal Uma, Liu Yeqiang, Gellen Emese
Dátum:2018
ISSN:1610-0379
Megjegyzések:Herpes simplex virus (HSV)-1 and -2 infections are highly prevalent worldwide. HSVinfection during pregnancy can result in neonatal herpes infection, which is characterizedby lifelong infection with periods of latency and reactivation. HSV can be acquiredby an infant during one of three periods: in utero (5 %), peripartum (85 %),or postnatal (10 %). Neonatal HSV is a rare but significant infection that may be associatedwith severe morbidity and mortality, especially if there is dissemination orcentral nervous system involvement. Diagnostic and therapeutic advances have led toa reduction in mortality and, to a lesser extent, improvement of neurodevelopmentaloutcomes, but further developments are still needed. It is essential to improve theclinician's ability to identify infants who are at increased risk of HSV infection and toprevent mother-to-child transmission. The development of novel antiviral agents withhigher efficacy is a worthwhile aim for the future.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Journal of the German Society of Dermatology. - 16 : 6 (2018), p. 685-692. -
További szerzők:Keyal, Uma Liu, Yeqiang Gellén Emese (1986-) (bőrgyógyász)
Pályázati támogatás:K 120206
OTKA
GINOP-2.3.2-15-2016-00005
GINOP
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