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001-es BibID:BIBFORM077848
035-os BibID:(PMID)30101988 (Scopus)85052790800 (WOS)000450406900003
Első szerző:Guttman András (vegyészmérnök)
Cím:Authors' Reply to the Commentary in the journal of Electrophoresis regarding "The effect of simulated space radiation on the N-glycosylation of human immunoglobulin G1" by J.J. Bevelacqua and S.M.J. Mortazavi / Andras Guttman, Szabolcs Szilasi, Boglarka Donczo, Mate Szarka
Dátum:2018
ISSN:0173-0835 1522-2683
Megjegyzések:By reading the commentary of Bevelacqua and Mortazavi regarding our recently published paper titled as "The effect of simulated space radiation on the N?glycosylation of human immunoglobulin G1"[1], we are afraid that some of the important messaging aspects of our paper might not have been articulated adequately to be fully understandable for a wider audience, i.e., not separation scientists. First, we should clarify that complete space radiation description was not the goal of this paper. In this short communication we only intended to show the effect of simulated space radiation on the conserved N?glycosylation of IgG1 molecules with the goal to understand if they could be utilized as disease biomarkers during longer space missions, similar to that as they are currently used here on Earth, e.g. for autoimmune disease or aging markers. Therefore, no discussion was given about any biological effects either as our study only investigated the qualitative effects of proton irradiation on the N?linked carbohydrate decomposition of IgG type 1 molecules with the intent of suggesting them to be used as biomarkers during deep space travel. Radioadaptation was never an issue in our study for the reasons mentioned above.
Tárgyszavak:Orvostudományok Elméleti orvostudományok szerkesztői levél
folyóiratcikk
Glycans
IgG
Space
Megjelenés:Electrophoresis. - 39 : 22 (2018), p. 2851-2853. -
További szerzők:Szilasi Szabolcs Döncző Boglárka (1987-) (biológiatanár-földrajztanár) Szarka Máté (1990-)
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