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001-es BibID:	BIBFORM083182
Első szerző:	Vitale, Salvatore Giovanni
Cím:	From hysteroscopy to laparoendoscopic surgery : what is the best surgical approach for symptomatic isthmocele? A systematic review and meta-analysis / Salvatore Giovanni Vitale, Artur Ludwin, George Angelos Vilos, Péter Török, Jan Tesarik, Amerigo Vitagliano, Ricardo Bassil Lasmar, Benito Chiofalo
Dátum:	2020
ISSN:	0932-0067 1432-0711
Megjegyzések:	Purpose To investigate the effectiveness and risks of different surgical therapies for isthmocele in symptomatic women with abnormal uterine bleeding, infertility, or for the prevention of obstetric complications, considering safety and surgical complications. Methods PubMed/MEDLINE, Scopus, Embase, Science Direct, and Cochrane Library were systematically searched (n? CRD4201912035) for original articles on the surgical treatment of isthmocele published between 1950 and 2018. Data synthesis was completed using MedCalc 16.4.3. The body of evidence was assessed using the GRADE methodology. Results We retrieved 33 publications: 28 focused on a single surgical technique, and five comparing different techniques. Meta-analysis showed an improvement of symptoms in 85.00% (75.05?92.76%) of women after hysteroscopic correction, 92.77% (85.53?97.64%) after laparoscopic/robotic correction, and 82.52% (67.53?93.57%) after vaginal correction. Hysteroscopic surgery was associated with the lowest risk of complications (0.76%, 0.20?1.66%). Conclusions We found adequate evidence supporting the use of surgery for the treatment of symptomatic isthmocele, as it was found to improve the bleeding symptoms in more than 80% of patients. Differently, we found a lack of evidence regarding the role of surgery with the purpose of improving fertility or reducing the risk of obstetric complications in women with asymptomatic isthmocele. The hysteroscopic correction of isthmocele may be the safest and most effective strategy in those patients with adequate residual myometrial thickness overlying the isthmocele. Laparoscopic and vaginal surgeries may be the preferred options for patients with a thinner residual myometrium over the defect (< 2.5 mm) and when hysteroscopic treatment is inconclusive.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Vaginal repair Niche Laparoscopy Isthmocele Hysteroscopy Caesarean scar defect
Megjelenés:	Archives of Gynecology And Obstetrics. - 301 : 1 (2020), p. 33-52. -
További szerzők:	Ludwin, Artur Vilos, George Török Péter (1975-) (szülész-nőgyógyász) Tesarik, Jan Vitagliano, Amerigo Lasmar, Ricardo Bassil Chiofalo, Benito
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