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001-es BibID:	BIBFORM083734
Első szerző:	Vitale, Salvatore Giovanni
Cím:	Ulipristal Acetate Before Hysteroscopic Myomectomy : a Systematic Review / Salvatore Giovanni Vitale, Simone Ferrero, Salvatore Caruso, Fabio Barra, Alejandro Marín-Buck, George Angelos Vilos, Amerigo Vitagliano, Péter Török, Michal Ciebiera, Antonio Cianci
Dátum:	2020
ISSN:	0029-7828
Megjegyzések:	Purpose: The aim of this review is to provide an overview of the literature about the effects of ulipristal acetate (UPA) administration prior to hysteroscopic myomectomy. Methods: We performed a systematic literature search in PubMed/MEDLINE and Embase for original studies written in English (registered in PROSPERO - CRD42018092201), using the terms 'hysteroscopy' AND 'ulipristal acetate' published up to September 2018. Original articles about UPA treatment prior to hysteroscopic myomectomy (randomized, observational, retrospective studies) were considered eligible. Results: Our literature search produced 32 records. After exclusions, 4 studies were included showing the following results: a) hysteroscopic myomectomy is not negatively affected by UPA pretreatment; b) UPA increases the probability of successfully performing complete myomectomy even in highly complex procedures; c) UPA pretreatment decreases the duration of the procedure and improves patient satisfaction at 3-months post-surgery. Conclusions: UPA pretreatment does not seem to be associated with negative outcomes of hysteroscopic myomectomy and it can improve the surgical outcomes in difficult cases. Once the concerns on the potential hepatotoxicity of UPA are resolved, high-quality prospective randomized controlled trials should be implemented to investigate its efficacy and benefits in a larger patient cohort.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Hysteroscopy Myomectomy Ulipristal acetate Uterine fibroids
Megjelenés:	Obstetrical & Gynecological Survey. - 75 : 2 (2020), p. 127-135. -
További szerzők:	Ferrero, Simone Caruso, Salvatore Barra, Fabio Marín-Buck, Alejandro Vilos, George Vitagliano, Amerigo Török Péter (1975-) (szülész-nőgyógyász) Ciebiera, Michał Cianci, Antonio
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