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001-es BibID:	BIBFORM098125
Első szerző:	Sipiczki Mátyás (biológus)
Cím:	Splitting of the fission yeast septum / Matthias Sipiczki
Dátum:	2007
ISSN:	1567-1356 1567-1364
Megjegyzések:	In cell-walled organisms, a cross wall (septum) is produced during cytokinesis, which then splits in certain organisms to allow the daughter cells to separate. The formation and the subsequent cleavage of the septum require wall synthesis and wall degradation, which need to be strictly coordinated in order to prevent cell lysis. The dividing fission yeast (Schizosaccharomyces) cell produces a three-layered septum in which the middle layer and a narrow band of the adjacent cell wall can be degraded without threatening the integrity of the separating daughter cells. This spatially very precise process requires the activity of the Agn1p 1,3-?-glucanase and the Eng1p 1,3-?-glucanase, which are localized to the septum by a complex mechanism involving the formation of a septin ring and the directed activity of the exocyst system. The Sep1p-Ace2p transcription-factor cascade regulates the expression of many genes producing proteins for this complex process. Recent advances in research into the molecular mechanisms of separation and its regulation are discussed in this review.
Tárgyszavak:	Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk cell separation cytokinesis septum cell wall Schizosaccharomyces cell cycle
Megjelenés:	Fems Yeast Research. - 7 : 6 (2007), p. 761-770. -
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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