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001-es BibID:BIBFORM100160
035-os BibID:(WOS)000750946900001 (Scopus)85125531096
Első szerző:Drosos, George C.
Cím:EULAR recommendations for cardiovascular risk management in rheumatic and musculoskeletal diseases, including systemic lupus erythematosus and antiphospholipid syndrome / Drosos George C., Vedder Daisy, Houben Eline, Boekel Laura, Atzeni Fabiola, Badreh Sara, Boumpas Dimitrios T., Brodin Nina, Bruce Ian N., González-Gay Miguel Ángel, Jacobsen Sren, Kerekes György, Marchiori Francesca, Mukhtyar Chetan, Ramos-Casals Manuel, Sattar Naveed, Schreiber Karen, Sciascia Savino, Svenungsson Elisabet, Szekanecz Zoltan, Tausche Anne-Kathrin, Tyndall Alan, van Halm Vokko, Voskuyl Alexandre, Macfarlane Gary J., Ward Michael M., Nurmohamed Michael T., Tektonidou Maria G.
Dátum:2022
ISSN:0003-4967
Megjegyzések:Objective To develop recommendations for cardiovascular risk (CVR) management in gout, vasculitis, systemic sclerosis (SSc), myositis, mixed connective tissue disease (MCTD), Sjögren's syndrome (SS), systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS). Methods Following European League against Rheumatism (EULAR) standardised procedures, a multidisciplinary task force formulated recommendations for CVR prediction and management based on systematic literature reviews and expert opinion. Results Four overarching principles emphasising the need of regular screening and management of modifiable CVR factors and patient education were endorsed. Nineteen recommendations (eleven for gout, vasculitis, SSc, MCTD, myositis, SS; eight for SLE, APS) were developed covering three topics: (1) CVR prediction tools; (2) interventions on traditional CVR factors and (3) interventions on disease-related CVR factors. Several statements relied on expert opinion because high-quality evidence was lacking. Use of generic CVR prediction tools is recommended due to lack of validated rheumatic diseases-specific tools. Diuretics should be avoided in gout and beta-blockers in SSc, and a blood pressure target <130/80 mm Hg should be considered in SLE. Lipid management should follow general population guidelines, and antiplatelet use in SLE, APS and large-vessel vasculitis should follow prior EULAR recommendations. A serum uric acid level <0.36 mmol/L (<6 mg/dL) in gout, and disease activity control and glucocorticoid dose minimisation in SLE and vasculitis, are recommended. Hydroxychloroquine is recommended in SLE because it may also reduce CVR, while no particular immunosuppressive treatment in SLE or uratelowering therapy in gout has been associated with CVR lowering. Conclusion These recommendations can guide clinical practice and future research for improving CVR management in rheumatic and musculoskeletal diseases
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Annals Of The Rheumatic Diseases. - 81 : 6 (2022), p. 768-779. -
További szerzők:Vedder, Daisy Houben, Eline Boekel, Laura Atzeni, Fabiola Badreh, Sara Boumpas, Dimitrios Brodin, Nina Bruce, Ian N. Gonzalez-Gay, Miguel A. Jacobsen, Sren Kerekes György (1973-) (belgyógyász, kardiológus, angiológus) Marchiori, Francesca Mukhtyar, Chetan Ramos-Casals, Manuel Sattar, Naveed Schreiber, Karen Sciascia, Savino Svenungsson, Elisabet Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Tausche, Anne-Kathrin Tyndall, Alan van Halm, Vokko Voskuyl, Alexandre Macfarlane, Gary J. Ward, Michael M. Nurmohamed, Michael T. Tektonidou, Maria G.
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