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001-es BibID:	BIBFORM100860
Első szerző:	Árnyasi Mariann (agrármérnök)
Cím:	Investigation of polymorphisms and association of the ABCG2 gene with milk production traits in sheep / M. Árnyasi, I. Komlósi, M. P. Kent, L. Czeglédi, G. Gulyás, A. Jávor
Dátum:	2013
ISSN:	1871-1413
Megjegyzések:	The ATP-binding casette sub-family G member 2 (ABCG2) gene was chosen as a candidate gene influencing milk production traits in sheep based on its function and chromosomal localization. A number of fragments were sequenced, including the 3·UTR region, 16 exons, and regions within introns 4, 5 and 6, in samples collected from 11 Awassi and 2 Gyimesi Racka sheep. A single 35-base insertion/deletion, and a total of 13 single nucleotide polymorphisms (SNPs) were identified. SNP mutations found in exons (n=3) were synonymous. Two SNPs (g.703T>C, c.863+40G>A) and the insertion/deletion (c.683-80_46del) were chosen for further investigation, and an association study between these three polymorphisms and milk production traits was performed in both breeds (Awassi n=310, Gyimesi Racka n=75). The analysis revealed significant effect of two of the studied SNPs in Gyimesi Racka. Mutation g.703T>C showed significant effect on protein percentage (p<0.05) while the c.683-80_46del had a significant effect on somatic cell score (p<0.01). However, further studies are needed to evaluate these possible associations more effectively.
Tárgyszavak:	Agrártudományok Állattenyésztési tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk ABCG2 gene Milk production Sheep
Megjelenés:	Livestock Science. - 154 : 1-3 (2013), p. 64-68. -
További szerzők:	Komlósi István (1960-) (agrármérnök) Kent, M. P. Czeglédi Levente (1977-) (agrármérnök) Gulyás Gabriella (1985-) (agrár) Jávor András (1952-) (agrármérnök)
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