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001-es BibID:BIBFORM107424
Első szerző:Jambrovics Károly (biológus, gyógyszer-biotechnológus)
Cím:Immune response mechanisms in blood transfusion / Jambrovics Károly
Dátum:2022
Megjegyzések:In the case of transfusing blood into the recipient, donor blood of the appropriate type is passed by gravity from a container down through a plastic tube and into a vein of the recipient's arm. The procedure is accomplished slowly, and two hours may be needed to infuse 450 mL of blood into the recipient. After double-checking labels on the bags of blood that are about to be given to ensure the units are intended for that recipient, the health care practitioner gives the blood to the recipient slowly, generally over 1 to 4 hours for each unit of blood. Because most adverse reactions occur during the first 15 minutes of the transfusion, the recipient is closely observed at first. To minimize the chance of an adverse reaction during a transfusion, health care practitioners take several precautions. Before starting the transfusion, usually a few hours or even a few days beforehand, the person is cross-matched with the donor blood (not done for transfusions of plasma or platelets). Transfusion-related acute lung injury (TRALI), is caused by antibodies in the donor's plasma. This reaction may cause serious breathing difficulties. This complication is the second most common cause of transfusion-related death. It occurs in 1 in 5,000 to 1 in 10,000 transfusions, but many cases are mild and so may not be diagnosed. Most people with mild to moderate lung injuries are given oxygen and other treatments that aim to support breathing until the lungs heal. Using plasma donated by men reduces the risk of having this reaction. Transfusion-associated circulatory overload (TACO) is a common transfusion reaction in which pulmonary edema develops primarily due to volume excess or circulatory overload. TACO is characterized by pulmonary hydrostatic (cardiogenic) edema, whereas TRALI presents as pulmonary permeability edema (noncardiogenic). The pathophysiology of both syndromes is complex and incompletely understood.
Tárgyszavak:Orvostudományok Elméleti orvostudományok előadáskivonat
könyvrészlet
Megjelenés:"Technology Update for Preventing Blood Transfusion Reactions". - p. 2253
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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