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001-es BibID:BIBFORM112140
035-os BibID:(Scopus)85160230345
Első szerző:Fekete Mónika
Cím:First booster dose uptake of COVID-19 vaccine and diseaserelated factors in chronic obstructive pulmonary disease - a cross-sectional survey in Hungary / Monika Fekete, Alpar Horvath, Balazs Santa, Gabor Tomisa, Gergő Szollosi, Janos Tamas Varga
Dátum:2023
ISSN:2224-5820 2224-5839
Megjegyzések:Background: In chronic obstructive pulmonary disease (COPD), uptake of the coronavirus disease 2019 (COVID-19) booster vaccine is important, as they are more likely to develop serious complications. Our aim was to investigate the uptake rate of first booster vaccination against COVID-19 among COPD patients and to identify other related factors of vaccine uptake. Methods: We conducted a multicenter survey of COPD patients in Hungary by region: eastern, western and central ones from 15 November 2021. Respiratory function test results, anthropometric data and vaccination status were recorded for 1,510 randomly selected patients over 35 years of age. Multiple logistic regression analysis was used to determine factors associated with uptake of COVID-19 first booster dose vaccines. Results: The average age was 67 [61?72] years, for men it was: 67 [62?73] and 66 [60?72] years for women, with a sample of 47.95% men and 52.05% women. The uptake rate of the COVID-19 first booster vaccine during the study period was 62.45%. Comparing patients who received the 3rd vaccine with those who did not receive the 3rd vaccine, the difference was significant in quality of life: COPD Assessment Test (CAT): 16 [11?21] vs. 14 [10?19], P<0.001, modified Medical Research Council (mMRC) dyspnea scale: 2 [2?2] vs. 2 [1?2], P=0.01 and in the number of moderate exacerbations: 1 [0?1] vs. 0 [0?1], P=0.04. In addition, who did not take the third vaccination significantly more people were hospitalized for acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (16 vs. 0, P<0.001) and almost the same proportion (n=14) required pulmonary outpatient rehabilitation for post-COVID symptoms. The factors that were most associated with higher COVID-19 vaccine first booster dose uptake were older age [odds ratio (OR): 1.06; 95% confidence interval (CI): 1.04?1.08], male gender (OR: 0.74; 95% CI: 0.57?0.96), absence of previous COVID-19 infection (OR: 0.34; 95% CI: 0.23-0.51). Conclusions: The uptake rate of the COVID-19 booster vaccine among COPD patients in Hungary is lower than the target, and is associated with disease-related factors, and age, sex, previous COVID infection. The global COVID-19 vaccination target is 70% and 100% for elderly, vulnerable patients. Highlighting the importance of taking booster vaccine(s) should be a priority for health workers. Keywords: Chronic obstructive pulmonary disease (COPD); coronavirus disease 2019 (COVID-19); vaccine uptake; COVID-19 vaccine first booster
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
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Megjelenés:Annals of Palliative Medicine. - 12 : 3 (2023), p. 516-528. -
További szerzők:Horváth Alpár Sánta Balázs Tomisa Gábor Szőllősi Gergő József (1991-) (népegészségügyi ellenőr, népegészségügyi szakember) Varga János Tamás (Budapest)
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