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001-es BibID:	BIBFORM113269
035-os BibID:	(WoS)000882514800006 (scopus)85141235387 (cikkazonosító)111805
Első szerző:	Botsi, Eirini
Cím:	Association of diet quality with glycemia, insulinemia, and insulin resistance in families at high risk for type 2 diabetes mellitus in Europe : Feel4 Diabetes Study / Botsi E., Karatzi K., Mavrogianni C., Kaloyan Tsochev, Esther M. González-Gil, Radó S., Kivelä J., Wikström K., Cardon G., Rurik I., Liatis S., Tsvetalina Tankova, Violeta Iotova, Luis A. Moreno, Makrillakis K., Manios Y., Tsigos C.
Dátum:	2023
ISSN:	0899-9007
Megjegyzések:	Objective The aim of the present study was to investigate the association of diet quality with fasting glycemia, insulinemia, and insulin resistance in a cross-sectional sample of adults from families at high risk for type 2 diabetes mellitus (T2DM) from six European countries, taking into account their socioeconomic status (SES). Methods Baseline data from non-diabetic adults from the Feel4 Diabetes study were used and diet was assessed by the Healthy Diet Score (HDS). Insulin resistance (IR) was determined by homeostasis model assessment of IR (HOMA-IR). Sociodemographic and lifestyle characteristics were assessed through standardized questionnaires. Multiple linear regressions were adjusted for many confounders, in the total sample and by SES category. Results In 1980 adults, the third tertile of diet quality was inversely associated with insulin levels (?1.48; 95% confidence interval [CI], ?2.34 to 0.62), and HOMA-IR (?0.33; 95% CI, ?0.57 to 0.09), yet with no statistically significant results for glucose levels. In the SES subgroup analysis, in the high SES group, both second and third diet score tertiles were inversely associated with insulin levels (?1.81; 95% CI, ?2.66 to 0.95) and HOMA-IR values (?0.45; 95% CI ?0.69 to 0.21), independent of age, sex, smoking and body mass index. No such associations were observed for glucose levels in the high SES group and for all indices in the low SES group. Conclusion In adults from families at high risk for T2DM, higher diet quality was negatively associated with fasting insulin levels and IR, only in the high SES group and not in the low SES group. Future larger studies may be able to explore further this association, as well as the potential factors that mitigate its strength in the low SES groups.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Nutrition. - 105 (2023), p. 1-6. -
További szerzők:	Karatzi, Kalliopi Mavrogianni, Christina Tsochev, Kaloyan González-Gil, Esther Radó Sándor Istvánné (1976-) (diplomás ápoló) Kivelä, Jemina Wikström, Katja Cardon, Greet Rurik Imre (1953-) (háziorvos, foglalkozás-egészségügyi szakorvos, urológus) Liatis, Stavros Tankova, Tsvetalina Iotova, Violeta Moreno, Luis A. Makrilakis, Konstantinos Manios, Yannis Tsigos, Constantine
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