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001-es BibID:	BIBFORM113522
035-os BibID:	(cikkazonosító)e10605 (Scopus)85162004368
Első szerző:	Toumaj, Shiva
Cím:	Targeted-release budesonide in immunoglobulin A nephropathy : a mini-review / Toumaj Shiva, Alimohammadi Shahrzad, Ghasemi Maryam, Shayanpour Shokouh
Dátum:	2023
ISSN:	2345-4202
Megjegyzések:	Immunoglobulin A nephropathy is the most common kind of primary glomerulonephritis worldwide and one of the main causes of renal failure. Systemic corticosteroid therapy may protect against renal deterioration in IgA nephropathy; however, it is not often advised for long-term treatment due to possible side effects. Recent studies present promising results of the new targeted-release formulation of budesonide that delivers the drug to the distal ileum to reduce side effects for patients with IgA nephropathy. In this paper, we highlighted the potential benefits of budesonide as a treatment option for IgA nephropathy and the need for additional studies to confirm its effectiveness. The lack of alternative treatments to prevent renal deterioration without other systemic side effects motivated us to gather relevant information to fill this gap. In this brief overview, we have reviewed some of the most recently published studies regarding how budesonide protects against IgA nephropathy. Studies reveal that budesonide might significantly decrease proteinuria, hematuria, and creatinine level while maintaining normal renal function. Though, a limited number of trials have been established to date, and further investigations are needed to confirm the benefit of the new targeted-release budesonide in treating IgA nephropathy
Tárgyszavak:	Orvostudományok Elméleti orvostudományok beszámoló folyóiratcikk Budesonide Corticosteroids End-stage kidney disease Glomerulonephritis IgA nephropathy Immunosuppressive therapy
Megjelenés:	Journal of Nephropharmacology. - 12 : 2 (2023), p. 1-3. -
További szerzők:	Alimohammadi, Shahrzad (1991-) (Gyógyszerész) Ghasemi, Maryam Shayanpour, Shokouh
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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