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001-es BibID:BIBFORM115138
035-os BibID:(WoS)000650730000001 (Scopus)85105193059 (cikkazonosító)2407
Első szerző:Bungau, Simona
Cím:Withaferin A-A Promising Phytochemical Compound with Multiple Results in Dermatological Diseases / Simona Bungau, Cosmin Mihai Vesa, Areha Abid , Tapan Behl, Delia Mirela Tit, Anamaria Lavinia Purza, Bianca Pasca, Laura Maghiar Todan, Laura Endres
Dátum:2021
ISSN:1420-3049
Megjegyzések:Withaferin A (WFA) was identified as the most active phytocompound of the plant Withania somnifera (WS) and as having multiple therapeutic/ameliorating properties (anticancer, antiangiogenic, anti-invasive, anti-inflammatory, proapoptotic, etc.) in case of various diseases. In drug chemistry, WFA in silico approaches have identified favorite biological targets, stimulating and accelerating research to evaluate its pharmacological activity-numerous anticancer effects manifested in various organs (breast, pancreas, skin, colon, etc.), antivirals, anti-infective, etc., which are not yet sufficiently explored. This paper is a synthesis of the most relevant specialized papers in the field that are focused on the use of WFA in dermatological diseases, describing its mechanism of action while providing, at the same time, details about the results of its testing in in vitro/in vivo studies.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Withania somnifera
withaferin A
dermatology
dermatological disorders
melanoma
Ayurvedic medicine
Megjelenés:Molecules. - 26 : 9 (2021), p. 1-14. -
További szerzők:Vesa, Cosmin Mihai Abid, Areha Behl, Tapan Tit, Delia Mirela Purza, Anamaria Lavinia Pasca, Bianca Todan, Laura Maghiar Endres Laura
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