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001-es BibID:BIBFORM117940
035-os BibID:(cikkazonosító)175 (WoS)001139768900001 (Scopus)85181965425
Első szerző:Bálint Ádám
Cím:Spatiotemporal Distribution of PRRSV-1 Clades in Hungary with a Focus on the Era of Disease Eradication / Ádám Bálint, Szilvia Jakab, Eszter Kaszab, Szilvia Marton, Krisztián Bányai, Sándor Kecskeméti, István Szabó
Dátum:2024
ISSN:2076-2615
Megjegyzések:Porcine reproductive and respiratory syndrome (PRRS) is the cause of the most severe economic losses in the pig industry worldwide. PRRSV is extremely diverse in Europe, which poses a significant challenge to disease control within a country or any region. With the combination of phylogenetic reconstruction and network analysis, we aimed to uncover the major routes of the dispersal of PRRSV clades within Hungary. In brief, by analyzing >2600 ORF5 sequences, we identified at least 12 clades (including 6 clades within lineage 1 and 3 clades within lineage 3) common in parts of Western Europe (including Denmark, Germany and the Netherlands) and identified 2 novel clades (designated X1 and X2). Of interest, some genetic clades unique to other central European countries, such as the Czech Republic and Poland, were not identified. The pattern of PRRSV clade distribution is consistent with the route of the pig trade among countries, showing that most of the identified clades were introduced from Western Europe when fatteners were transported to Hungary. As a result of rigorous implementation of the national eradication program, the swine population was declared officially free from PRRSV. This map of viral diversity and clade distribution will serve as valuable baseline information for the maintenance of PRRSV-free status in the post-eradication era.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
disease eradication
genetic diversity
molecular epidemiology
phylogeny
porcine reproductive and respiratory syndrome
PRRS
Megjelenés:Animals. - 14 : 1 (2024), p. 1-8. -
További szerzők:Jakab Szilvia Kaszab Eszter (1989-) (biológus) Marton Szilvia Bányai Krisztián Kecskeméti Sándor Szabó István
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