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001-es BibID:	bibEBI00007156
Első szerző:	Sipiczki Mátyás (biológus)
Cím:	Growth polarity transitions in a dimorphic fission yeast / M. Sipiczki, K. Takeo, A. Grallert
Dátum:	1998
ISSN:	1350-0872 1465-2080
Megjegyzések:	Fission yeast cells grow by extension at the ends (poles) and divide by transverse fission. It has previously been reported that Schizosaccharomyces japonicus var. japonicus can switch to unipolar, filamentous growth. Here it is shown that the yeast-to-mycelium transition is a gradual process involving a changeover to unipolar growth associated with asymmetric divisions, the development of large polarly located vacuoles, the modifications of the actin and microtubular cytoskeleton and the repression of cell separation after division. High concentrations of glucose in the medium or supplementation of the medium with caffeine or cAMP support the bipolar yeast phase, inhibit the transition to the mycelial phase and induce the conversion of hyphae to yeasts. These effects suggest that cAMP may be involved in the regulation of dimorphism. Temperatures below 18 °C or over 35 °C are restrictive for the mycelial phase and provoke a return to yeast phase.
Tárgyszavak:	Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban cAMP polarity vacuolation Schizosaccharomyces dimorphism
Megjelenés:	Microbiology (Reading, England). - 144 (1998), p. 3475-3488. -
További szerzők:	Takeo Kanji Grallert Ágnes (genetikus)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
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