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1.

001-es BibID:BIBFORM019255
Első szerző:Árkosy Péter (általános sebész, mellkassebész)
Cím:New reconstructive surgery of remnant pancreas in cases of cancer of Vater's papilla / Peter Árkossy, Peter Tóth, Istvan Kovács, Peter Sápy
Dátum:2002
ISSN:0172-6390
Megjegyzések:BACKGROUND/AIMS: The radical surgical procedure for treatment of the carcinoma of papilla of Vater is the pancreatoduodenectomy. The mortality rate of the surgery highly decreased in the last decade, nevertheless there are complications related to the complication of anastomosis of the remnant pancreas. METHODOLOGY: The authors introduce a new reconstructional procedure to decrease the complications. After the removal of the pancreatic head and body an end-to-side anastomosis was performed between the pancreatic duct and a Roux-en jejunal loop. The second anastomosis of the procedure was an end-to-side choledochojejunostomy, the third was an end-to-side duodenojejunostomy. The duodenojejunostomy is about 40 cm from the pancreatic anastomosis, keeping food far from the pancreas with the help of peristaltic waves. This method was applied in 6 patients. RESULTS: It was found that the new reconstructional procedure had generally favorable results without complication. CONCLUSIONS: This method of reconstruction allows for spontaneous closure and safe drainage of potential insufficient pancreaticojejunostomy. The recovered patients support future favorable usage of this new reconstructional surgical procedure.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Hepato-Gastroenterology. - 49 : 43 (2002), p. 255-257. -
További szerzők:Tóth Péter (sebész) Kovács István (sebész) Sápy Péter (1942-) (sebész)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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2.

001-es BibID:BIBFORM019276
Első szerző:Hallay Judit (aneszteziológus, intenzív terápiás szakorvos, gyermekgyógyász)
Cím:Early jejunal nutrition and changes in the immunological parameters of patients with acute pancreatitis / J. Hallay, G. Kovács, K. Szatmári, A. Bakó, Zs. Szentkereszty, G. Lakos, S. Sipka, P. Sápy
Dátum:2001
ISSN:0172-6390
Megjegyzések:BACKGROUND/AIMS: We have compared the effects of glutamine-rich Stresson Multi Fibre and of Nutrison Fibre nutrients on the changes of some immunological parameters of 16 patients with acute pancreatitis. Laboratory parameters included: total protein, albumin, prealbumin, retinol binding protein, IgG, IgA, IgM, IgE, complement components: C3, C4, acute phase proteins: C-reactive protein, transferrin, CD-markers of peripheral lymphocytes and activity of peripheral phagocytes. METHODOLOGY: Nine patients were supplied with Stresson Multi Fibre and 7 patients with Nutrison Fibre, using a nasojejunal tube. The levels of serum proteins were measured with laser nephelometry, the CD markers of lymphocytes with flow cytometry and the phagocytic activity with chemiluminescence. RESULTS: The treatment with glutamine-rich Stresson resulted in significant elevations in the serum levels of IgG, retinol binding protein, compared to the effects of Nutrison Fibre. In addition, the recovery of treated patients was significantly shorter in the Stresson Multi Fibre group than in the Nutrison Fibre group. CONCLUSIONS: The Stresson Multi Fibre nutrient treatment of patients treated for acute pancreatitis seems to have clinical benefit based upon the fast recovery of IgG, IgM proteins which take part in the immunological defense mechanisms.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Hepato-Gastroenterology. - 48 : 41 (2001), p. 1488-1492. -
További szerzők:Kovács Gábor (orvos) Szatmári Katalin Bakó Andrea Szentkereszty Zsolt (1961-) (sebész) Lakos Gabriella (1963-) (laboratóriumi szakorvos, transzfúziológus, immunológus) Sipka Sándor (1945-) (laboratóriumi szakorvos) Sápy Péter (1942-) (sebész)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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3.

001-es BibID:BIBFORM019273
Első szerző:Hallay Judit (aneszteziológus, intenzív terápiás szakorvos, gyermekgyógyász)
Cím:Changes in the nutritional state and immune-serological parameters of esophagectomized patients fed jejunaly with glutamine-poor and glutamine-rich nutriments / Hallay J., Kovács G., Sz. Kiss S., Farkas M., Lakos G., Sipka S., Bodolay E., Sápy P.
Dátum:2002
ISSN:0172-6390
Megjegyzések:In our former study we investigated the effect of glutamine-rich (I) and glutamine-poor (II) jejunal diet in operated patients with acute pancreatitis. In the glutamine-rich diet group clinical benefit and fast recovery of IgG, IgM, serum proteins, retinol-binding protein, albumin could be measured. In the present study the effects of the two types of jejunal diets I and II have been compared on the basis of changes in some immune parameters of 36 patients treated with subtotal esophagectomy for malignancy. METHODOLOGY: In randomized controlled trial data of two groups, I. patients with glutamine-rich Stresson Multi Fibre diet (23 patients) and II. patients with Nutrison Multi Fibre glutamine-poor diet (13 patients) were analyzed. Levels of serum proteins were measured by laser nephelometry, CD markers of lymphocytes by flow cytometry, phagocyte activity by chemiluminescence. RESULTS: Level of proteins decreased on the 2nd postoperative day in both groups, then gradually increased postoperatively. In increase of level of serum protein, retinol-binding protein, prealbumin there was no difference between the two groups. CONCLUSIONS: In patients treated with subtotal esophagectomy, the glutamine-rich enteric diet did not result in faster recovery in levels of prealbumin, retinol-binding protein, immunoglobulins and in outcome of patients than the glutamine-poor nutriment.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Hepato-Gastroenterology. - 49 : 48 (2002), p. 1555-1559. -
További szerzők:Kovács Gábor (orvos) Kiss Sándor, Sz. (1946-) (sebész) Farkas Mónika Lakos Gabriella (1963-) (laboratóriumi szakorvos, transzfúziológus, immunológus) Sipka Sándor (1945-) (laboratóriumi szakorvos) Bodolay Edit (1950-) (belgyógyász, allergológus és klinikai immunológus) Sápy Péter (1942-) (sebész)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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4.

001-es BibID:BIBFORM019278
Első szerző:Kerekes László (sebész, háziorvos)
Cím:Evaluation of hemostatic changes and blood antioxidant capacity in acute and chronic pancreatitis / Kerekes László, Árkossy Péter, Altorjay István, Huszka Mariann, Kappelmayer János, Tóth Péter, Szentkereszty Zsolt, Sápy Péter
Dátum:2001
ISSN:0172-6390
Megjegyzések:We examined changes in hemostasis, in levels of total antioxidant capacity, and pancreatic enzymes (amylase, lipase) in patients with pancreatitis 1, 3 and 7 days after admission to the clinic, in order to evaluate the inflammatory processes in acute and chronic pancreatitis and to identify new prognostic markers. METHODOLOGY: The rate of CD62 expression--a marker of platelet hyperactivity--and the rate of platelet-leukocyte aggregates were measured by flow cytometry. The connection between the parameters measured and the severity of pancreatitis and also the differences of the parameters in acute and chronic pancreatitis were investigated. RESULTS: On the basis of previous studies it was assumed, that there is a connection between the level of parameters measured and the inflammatory process in the pancreas, and also between the defending processes of the body against free radicals. CONCLUSIONS: Based on our results, we suggest to extend the laboratory measurements to the investigation of hemostatic parameters. The measurement of plasma level of fibrinogen, von Willebrand factor and the rate of platelet activation is especially important.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Hepato-Gastroenterology. - 48 : 42 (2001), p. 1746-1749. -
További szerzők:Árkosy Péter (1962-) (általános sebész, mellkassebész) Altorjay István (1954-) (belgyógyász, gasztroenterológus, onkológus) Huszka Mariann Kappelmayer János (1960-) (laboratóriumi szakorvos) Tóth Péter (sebész) Szentkereszty Zsolt (1961-) (sebész) Sápy Péter (1942-) (sebész)
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5.

001-es BibID:BIBFORM018543
Első szerző:Sápy Péter (sebész)
Cím:Simple reconstructive method in cases of duodenum-preserving subtotal resection of the head of pancreas / Sápy Péter, Árkossy Péter, Szappanos Miklós
Dátum:1998
ISSN:0172-6390
Megjegyzések:Surgical treatment of chronic pancreatitis is either by ductal decompression, or resection of the pancreas. Among various resection operations the duodenum preserving resection of the head of pancreas is the newest surgical technique. This paper describes substances of our modified reconstructive method following resection of the pancreatic head, and the results of this procedure. METHODOLOGY: Duodenum preserving resection of the head of pancreas with a simple modified reconstruction was performed in 21 patients with chronic pancreatitis. Early and late results are herein evaluated. RESULTS: There was no mortality. The rate of complication was 28.5%. Considering late results, complete pain relief was achieved in 80% of patients. Body weight was unchanged in 50%, decreased in 15% and gained in 35% of patients. Progression of endocrine dysfunction (rate of diabetes mellitus and glucose tolerance impairment) was observed to a small degree two years (average follow-up) after the operation. CONCLUSION: Our procedure can be applied in the treatment of chronic pancreatitis, with low risk and relatively good late results.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Hepato-Gastroenterology. - 45 : 23 (1998), p. 1870-1873. -
További szerzők:Árkosy Péter (1962-) (általános sebész, mellkassebész) Szappanos Miklós
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6.

001-es BibID:BIBFORM018603
Első szerző:Sipka Sándor (laboratóriumi szakorvos)
Cím:Protecting effects of intravenous insoluble glycogen treatment on the experimental necrotizing acute pancreatitis of dogs / Sipka Sándor, Sápy Péter, Bot György, Furka István, Mikó Irén, Árkossy Péter, Dauda György, Szappanos Miklós, Kovács J., Lakos Gabriella, Szegedi Gyula
Dátum:1997
ISSN:0172-6390
Megjegyzések:We have studied the effects of insoluble glycogen applied intravenously on the experimental acute pancreatitis of dogs. METHODS: Experimental acute pancreatitis was induced by olive oil injected into the main pancreatic duct. The effects of insoluble glycogen were evaluated histologically and by measurements of levels of amylase, lipase in sera. The binding of endotoxin and secretable phospholipase A2 by insoluble glycogen were tested by isotopically labeled materials. RESULTS: Application of insoluble glycogen had beneficial effects on the experimental acute pancreatitis of dogs. CONCLUSION: The binding capacity on endotoxin and secretable phospholipase A2 could play the main role in the protection offered by insoluble glycogen.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Hepato-Gastroenterology. - 44 : 13 (1997), p. 127-132. -
További szerzők:Sápy Péter (1942-) (sebész) Bot György (1917-1998) (biokémikus, vegyész) Furka István (1935-2021) (sebész, urológus, kutatóorvos) Mikó Irén (1948-) (kutató sebész) Árkosy Péter (1962-) (általános sebész, mellkassebész) Dauda György Szappanos Miklós Kovács J. (pathológus) Lakos Gabriella (1963-) (laboratóriumi szakorvos, transzfúziológus, immunológus) Szegedi Gyula (1936-2013) (belgyógyász, immunológus)
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7.

001-es BibID:BIBFORM019341
Első szerző:Szentkereszty Zsolt (sebész)
Cím:Quality of life following acute necrotizing pancreatitis / Zsolt Szentkereszty, Ágnes Czimbalmos, Róbert Kotán, Szilárd Gulácsi, László Kerekes, Zsolt Nagy, Danie Czakó, Péter Sápy
Dátum:2004
ISSN:0172-6390
Megjegyzések:BACKGROUND/AIMS: The authors examine the quality of life of patients treated for acute necrotizing pancreatitis an average of 37.8 months following their illness. METHODOLOGY: The questionnaire used in the examinations was a version of the Short Form-36 (SF-36) which was adapted to a Hungarian environment and included additional questions regarding the patient's illness. During the treatment of the pancreatic necrosis, prophylactic antibiotic treatment, early nasojejunal feeding, percutaneous peripancreatic drainage, and late surgical necrectomy was used. Postoperatively the lavage of the closed omental bursa was performed. RESULTS: It was determined that 77.3% of patients considered their quality of life to be good or fair. Quality of life was considered worse in older patients, patients with complaints of abdominal distension and bowel problems, patients who had lost significant amounts of weight since their illness, patients with poor appetite, and patients who were female. CONCLUSIONS: The long-term result, and the quality of life after acute necrotizing pancreatitis is good.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Hepato-Gastroenterology. - 51 : 58 (2004), p. 1172-1174. -
További szerzők:Czimbalmos Ágnes Kotán Róbert (1975-) (sebész) Gulácsi Szilárd Kerekes László (sebész, háziorvos) Nagy Zsolt (orvos) Czakó Danie Sápy Péter (1942-) (sebész)
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8.

001-es BibID:BIBFORM019248
Első szerző:Szentkereszty Zsolt (sebész)
Cím:CT-guided percutaneous peripancreatic drainage: a possible therapy in acute necrotizing pancreatitis / Szentkereszty Z., Kerekes L., Hallay J., Czako D., Sápy P.
Dátum:2002
ISSN:0172-6390
Megjegyzések:To examine the effectiveness of therapeutic percutaneous drainage of peripancreatic fluid in the treatment of acute necrotizing pancreatitis. METHODOLOGY: Twenty-eight patients treated for serious acute necrotizing pancreatitis (19 male, 9 female; average age 47.3 years) took part in the study. The cause of acute necrotizing pancreatitis was alcohol abuse in 20 of the cases, gallstone disease in 7 cases, endoscopic retrograde cholangiopancreatography in 2 cases, trauma in one case, and 4 of the cases had unknown cause. In all cases preventative antibiotics were given as part of intensive therapy, early nasojejunal nutrition was used, and we endeavored to avoid surgery or to delay it depending on the case. The acute peripancreatic fluid was drained percutaneously. In total, percutaneous drainage was used in 12 patients. RESULTS: Of the 28 patients, only 3 patients recovered solely with conservative therapy, without drainage. Three patients recovered using only percutaneous drainage without surgery. In 9 patients surgery was necessary after percutaneous drainage was performed. In the remaining 13 patients, only surgical treatment was used, without percutaneous drainage. In total 20 reoperations were done in 10 patients. Of the 12 patients treated with percutaneous drainage, one patient died. The total mortality was 14.3%. CONCLUSIONS: In certain cases the percutaneous drainage of the acute peripancreatic fluid that collects in acute necrotizing pancreatitis is sufficient for the total recovery of acute necrotizing pancreatitis, in other cases can be used to postpone surgery.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Hepato-Gastroenterology. - 49 : 48 (2002), p. 1696-1698. -
További szerzők:Kerekes László (sebész, háziorvos) Hallay Judit (1949-) (aneszteziológus, intenzív terápiás szakorvos, gyermekgyógyász) Czakó Danie Sápy Péter (1942-) (sebész)
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9.

001-es BibID:BIBFORM019342
Első szerző:Vágvölgyi Attila
Cím:Near total hepatectomy in two steps for surgical treatment of liver metastasis of colorectal tumour / A. Vagvolgyi, I. Takacs, P. Arkossy, M. Peter, P. Sapy
Dátum:2003
ISSN:0172-6390
Megjegyzések:Liver resections for metastases of colorectal carcinomas are generally accepted. The 5-year survival rate is higher than 30 percent. Major resections can be performed safely with normal remnant liver. The liver regenerates following extended hepatectomies or other major resections. Authors operated on a 57-year-old man for a secondary liver tumor. The primary tumor was in the colon sigmoideum and sigma-resection was made at another hospital 16 months before. The metastasis was in the right lobe of the liver. Authors performed right extended hepatectomy. After systemic chemotherapy, 4.5 months later a new metastasis developed in the left lobe. Despite locoregional chemotherapy, chemoembolization and radiofrequency treatment, the tumor was still growing so a left lobectomy was performed. The patient is macroscopically tumor-free 17 months after the first hepatic resection. The interest in this case is that segments IV to VIII were removed first time, and segments II and III at the second liver resection. Liver regeneration after the first resection made the second operation possible. Only segment I of the original segments remained. Utilizing the regeneration of the liver we can make an effort to perform a complete tumor ablation in two steps.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Hepato-Gastroenterology. - 50 : 54 (2003), p. 2176-2178. -
További szerzők:Takács István (1963-) (sebész) Árkosy Péter (1962-) (általános sebész, mellkassebész) Péter Mózes (1936-) (radiológus) Sápy Péter (1942-) (sebész)
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