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001-es BibID:BIBFORM079829
035-os BibID:(cikkazonosító)AS05-056
Első szerző:Fekete Klára (neurológus)
Cím:Predictors of long-term outcome in patients with basilar artery occlusion : a single center study / K. Fekete, J. Toth, H. Mate, M. Sandor, H. Toth, L. Csiba, I. Fekete
Dátum:2019
Megjegyzések:Background and Aims: Basilar artery occlusion (BAO) is a fatal disease despite recanalization techniques and limited data is available of the factors predicting outcome. Methods: Data of 100 patients treated with BAO was collected prospectively between 2004 and 2018. Risk factors, neurological status, outcome (case fatality, 3-months-mRS, one-year-survival); cranial CT (posterior circulation ASPECT score), result of CT angiography; and the treatment modality was given. Results: Average age was 64.9 13.7 years, 54% male. The most remarkable risk factor was previous stroke (29%), 55% of it vertebrobasilar (58% mortality). The onset to treatment time was 4.23 2.85 hours. The pc-ASPECT score was 10 in 67%, 7 points 33%. BAO was in the proximal part in 17%, in half in 20%, total in 21% and only the top in 42%; respectively within its group the mortality was 53%, 45%, 62%, 38%. Intravenous thrombolysis happened in 43%, intraarterial in 27%, combined therapy in 18% and 12% was treated conservatively. Case fatality within the treatment group was respectively: 48.8%, 55.5%, 33.3%, and 66.6% (p ? 0.8). Symptomatic haemorrhage was not different among the recanalization groups (p ? 0.83). Total or partial recanalization was achieved in 39%. There was a favourable trend in the recanalization rate of intraarterial and combined groups (p ? 0.4). At 3 months 23% had mRS 0?2, 3?5 42%, 58% were dead. At one year 26% was alive. Conclusions: The top occlusion of the BA, combined therapy may influence favourably the outcome. Among the risk factors previous VB stroke has a high impact. Trial registration number: N/A
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
haemorrhage
Megjelenés:European Stroke Journal. - 4 : Suppl. 1 (2019), p. 740. -
További szerzők:Tóth Judit (1964-) (radiológus) Máté H. Sándor Mária (1979-) (etnográfus) Tóth H. Csiba László (1952-) (neurológus, pszichiáter) Fekete István (1951-) (neurológus, pszichiáter)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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2.

001-es BibID:BIBFORM046051
Első szerző:Schulte-Altedorneburg, Gernot
Cím:Detection of carotid artery stenosis by in vivo duplex ultrasound : correlation with planimetric measurements of the corresponding postmortem specimens / Gernot Schulte-Altedorneburg, Dirk W. Droste, Szabolcs Felszeghy, László Csiba, Vasile Popa, Katalin Hegedüs, József Kollár, László Módis, E. Bernd Ringelstein
Dátum:2002
ISSN:1120-9976
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Stroke. - 33 (2002), p. 2402-2407. -
További szerzők:Droste, Dirk W. Felszeghy Szabolcs Béla (1972-) (fogorvos, anatómus, kötőszövetbiológus) Csiba László (1952-) (neurológus, pszichiáter) Popa, Vasile Hegedűs Katalin (1946-2017) (ideggyógyász, neuropathológus) Kollár János (1962-) (pszichológus, klinikai és mentálhigiéniai szakpszichológus) Módis László (1939-) (anatómus, kötőszövetbiológus) Ringelstein, E. Bernd
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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3.

001-es BibID:BIBFORM015608
035-os BibID:12364728
Első szerző:Schulte-Altedorneburg, Gernot
Cím:Detection of carotid artery stenosis by in vivo duplex ultrasound: correlationwith planimetric measurements of the corresponding postmortem specimens / Gernot Schulte-Altedorneburg, Dirk W. Droste, Szabolcs Felszeghy, Laszlo Csiba, Vasile Popa, Katalin Hegedus, Jozsef Kollar, Laszlo Modis, E. Bernd Ringelstein
Dátum:2002
ISSN:0039-2499 (Linking)
Megjegyzések:BACKGROUND AND PURPOSE: The correct detection and quantification of carotidartery disease are of decisive impact on patient prognosis and adequatetreatment. In this study, we evaluated the ability of ultrasonography to detectand to grade carotid artery stenosis through a comparison of the in vivoultrasound findings with the planimetric analysis of the corresponding postmortemspecimens. METHODS: Shortly before their death, 59 critically ill neurologicalpatients (mean age, 70 years) were prospectively examined by extracranial andintracranial Doppler sonography and color-coded duplex ultrasound. Carotidstenosis was classified by hemodynamic and morphological ultrasound criteria.Carotid specimens were removed in toto during autopsy. Under standardizedconditions, specimens were redistended, sectioned, and histologically processed.Computerized planimetric measurements of the arteries were carried out andcompared with the ultrasound findings. Correlation of the ultrasound andpostmortem planimetric findings was available in 93 carotid bifurcations.RESULTS: Through both techniques, 46 carotid arteries were found to be normal.Steno-occlusive carotid lesions ranged from 8.5% to 100% lumen reduction.Overall, r=0.96 and adjusted R(2)=0.90. For the steno-occlusive carotid lesions,r=0.91. CONCLUSIONS: Extracranial and intracranial Doppler and color-coded duplexultrasound permits reliable detection and quantification of carotid arterystenoses and occlusions even under difficult examination conditions in criticallyill patients.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Adult
Aged
Aged, 80 and over
Blood Flow Velocity
Carotid Arteries/*pathology/physiopathology/*ultrasonography
Carotid Artery Thrombosis/classification/*pathology/*ultrasonography
Female
Hemodynamics
Humans
Hungary
Intracranial Hypertension/radiography
Male
Middle Aged
Predictive Value of Tests
Prospective Studies
Sensitivity and Specificity
Tomography, X-Ray Computed
Ultrasonography, Doppler, Color
Ultrasonography, Doppler, Transcranial
Vascular Patency
egyetemen (Magyarországon) készült közlemény
Megjelenés:Stroke. - 33 : 10 (2002), p. 2402-2407. -
További szerzők:Droste, Dirk W. Felszeghy Szabolcs Béla (1972-) (fogorvos, anatómus, kötőszövetbiológus) Csiba László (1952-) (neurológus, pszichiáter) Popa, Vasile Hegedűs Katalin (1946-2017) (ideggyógyász, neuropathológus) Kollár József (1950-) (radiológus) Módis László (1939-) (anatómus, kötőszövetbiológus) Ringelstein, E. Bernd
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
elektronikus elérés
DOI
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4.

001-es BibID:BIBFORM079828
035-os BibID:(cikkazonosító)AS24-058
Első szerző:Szegedi István (orvos)
Cím:The association of plasminogen activator inhibitor-1 (pai-1) 4g/5g polymorphism with the risk and prognosis of intracerebral hemorrhage / I. Szegedi, T. Arokszallasi, I. Fekete, K. Fekete, A. Nagy, F. Sarkady, E. G. Székely, K. R. Czuriga-Kovacs, E. Berenyi, Z. Bagoly, L. Csiba
Dátum:2019
Megjegyzések:Background and Aims: Non-traumatic intracerebral hemorrhage accounts for 10?15% of all strokes, but has much higher mortality than acute ischemic stroke (AIS). Plasminogen activator inhibitor-1 (PAI-1) is a natural inhibitor of fibrinolysis that protects against bleeding. PAI-1 5G/ 5G genotype is associated with lower PAI-1 levels, thus we hypothesized that it could be associated with the risk and outcome of intracerebral hemorrhage. Methods: Three populations were included in the study: 51 patients with primary intracerebral haemorrhage (PICH), 13 patients with AIS who suffered hemorrhagic transformation after intravenous thrombolysis (AIS-ICH), and 118 AIS patients without hemorrhagic events (AIS). PAI-1 4G/5G polymorphism was determined in all patients. Clinical data was registered on admission and day 7 post-event. Short-term outcome was defined according to NIHSS change at 7 days. Long-term outcome was measured by the modified Rankin Scale at 3 months. Results: The presence of PAI-1 5G allele was significantly more frequent in the AIS-ICH group as compared to the AIS and PICH cohorts and a population control cohort. PAI-1 4G/5G polymorphism had no effect on stroke severity or short-term outcome in either groups. In a binary backward logistic regression model including age, gender, BMI, NIHSS on admission, hypertension, hyperlipidaemia it was revealed that PAI-1 5G/5G genotype confers an independent, significant risk for post-lysis intracranial hemorrhage (OR:4.75, 95%CI:1.18-19.06, p ? 0.028). PAI-1 4G/5G polymorphism had no influence on mortality and long-term outcome in the studied patient cohorts. Conclusions: PAI-1 5G/5G genotype confers an independent, significant risk for post-lysis intracerebral haemorrhage.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
haemorrhage
Megjelenés:European Stroke Journal. - 4 : Suppl. 1 (2019), p. 470. -
További szerzők:Árokszállási Tamás (1988-) (neurológus) Fekete István (1951-) (neurológus, pszichiáter) Fekete Klára (1978-) (neurológus) Nagy A. Sarkady Ferenc (1982-) (laboratóriumi analitikus) Székely Edina Gabriella Czuriga-Kovács Katalin Réka (1981-) (neurológus) Berényi Ervin (1964-) (radiológus) Bagoly Zsuzsa (1978-) (orvos) Csiba László (1952-) (neurológus, pszichiáter)
Pályázati támogatás:GINOP-2.3.2-15-2016-00043
GINOP
NKFI-K120042
NKFI
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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